Mandelsure

Bezeichnung:Mandelsure

CAS-Nr90-64-2

Englisch Name:DL-Mandelic acid

CBNumberCB3287471

SummenformelC8H8O3

Molgewicht152.15

MOL-Datei90-64-2.mol

Synonyma

Mandelsure

Mandelsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	119-121 °C (lit.)
Siedepunkt	214.6°C (rough estimate)
alpha	[α]D20 -0.5～+0.5° (c=2, H2O)
Dichte	1.30
Dampfdruck	0.01 Pa (50 °C)
Brechungsindex	1.4810 (estimate)
storage temp.	Store below +30°C.
Löslichkeit	139g/l
pka	3.85(at 25℃)
Aggregatzustand	Crystals or Crystalline Powder
Farbe	White
PH	2.3 (10g/l, H2O)
Geruch (Odor)	faint odor
Optische Aktivität	[α]/D 0±1°, c = 5 in H2O
Wasserlöslichkeit	150 g/L (20 ºC)
Sensitive	Light Sensitive
Merck	14,5717
BRN	510011
InChIKey	IWYDHOAUDWTVEP-UHFFFAOYSA-N
LogP	0.5 at 23℃
CAS Datenbank	90-64-2(CAS DataBase Reference)
NIST chemische Informationen	Benzeneacetic acid, «alpha»-hydroxy-(90-64-2)
EPA chemische Informationen	Mandelic acid (90-64-2)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	36/37/38-22
S-Sätze:	22-24/25-37/39-26-36
WGK Germany	3
RTECS-Nr.	OO6300000
TSCA	Yes
HS Code	29181990

Gefahreninformationscode (GHS)

DL-Mandelic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White rhomboidal crystals, decompose when exposed to light. Soluble in ether and isopropanol, soluble in ethanol and water; R-form melting point is 133°C, [α]-159.73° (ethanol), gradually racemic at 160°C. S-form melting point is 133.8°C, [α]+156.57° (water).
Verwenden
Organic synthesis, medicine (urinary antiseptic).
Verwenden
DL-Mandelic acid may be used as an analytical reference standard for the determination of DL-mandelic acid in:
Human urine samples by high performance liquid chromatography (HPLC) equipped with ultraviolet (UV) detector.
Rat urine samples by gas chromatography-mass spectrometry (GC-MS) with selected ion monitoring (SIM) detection.
Definition
ChEBI: Mandelic acid is a 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups. It has a role as an antibacterial agent and a human xenobiotic metabolite. It is a 2-hydroxy monocarboxylic acid and a member of benzenes. It derives from an acetic acid. It is a conjugate acid of a mandelate. Exists in stereoisomeric forms. The properties are those of the dl-form.
synthetische
Mandelic acid can be prepared by the hydrolysis of amygdalin with sulfuric acid or of mandelonitrile with hydrochloric acid. The mandelonitrile can be prepared by the action of hydrocyanic acid on benzaldehyde, and by the action of sodium or potassium cyanide on the sodium bisulfite addition product of benzaldehyde. The procedure described differs from earlier methods in that the sodium bisulfite addition compound of benzaldehyde is prepared in the presence of sodium cyanide and the nitrile is formed immediately.
synthesis of mandelic acid
Allgemeine Beschreibung
DL-Mandelic acid is an aromatic hydrocarbon metabolite of styrene.
Hazard
Toxic by ingestion.
Flammability and Explosibility
Not classified
Sicherheitsprofil
Poison by intramuscular route. Moderately toxic by ingestion. Continued absorption can cause kidney irritation. When heated to decomposition it emits acrid smoke and irritating fumes.

DL-Mandelic acid Upstream-Materialien And Downstream Produkte

Mandelsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

90-64-2, DL-Mandelic acid Verwandte Suche:

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