TN ANTIGEN

TN ANTIGEN Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  TN ANTIGEN is Yellow Solid

• Verwenden

  TN ANTIGEN is a cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines

• Verwenden

  A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines.

• Definition

  ChEBI: O-(N-acetyl-alpha-D-galactosaminyl)-L-serine is a non-proteinogenic L-amino acid that is N-acetyl-alpha-D-galactosamine linked via an alpha glycosidic bond to the O at position 3 of L-serine. It has a role as a tumour antigen. It is a L-serine derivative and a non-proteinogenic L-alpha-amino acid.

• Allgemeine Beschreibung

  Tn antigen?is a truncated O-glycan, that is commonly noticed in colorectal cancer (CRC). It is usually expressed at high levels in cancer cells. Tn antigen is small in size and simple in structure. It has a non-physiological glycan structure in humans, hence it may be identified as foreign by the immune system.

• Biochem/physiol Actions

  Tn antigen stimulates colorectal cancer metastasis through the activation of epithelial-mesenchymal transition, mediated by H-Ras. It acts as a precursor to several significant complex O-glycans. Subpopulations of blood cells in all lineages carrying the Tn antigen results in a hematological disorder called Tn syndrome.

TN ANTIGEN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(41)Suppliers