Panthenol , DL-Form

Bezeichnung:Panthenol , DL-Form

CAS-Nr16485-10-2

Englisch Name:Panthenol

CBNumberCB3274109

SummenformelC9H19NO4

Molgewicht205.25

MOL-Datei16485-10-2.mol

Synonyma

Panthenol , DL-Form

Panthenol , DL-Form physikalisch-chemischer Eigenschaften

Schmelzpunkt	66-69 °C (lit.)
alpha	0°(c=5, H2O)
Siedepunkt	118-120 °C(Press: 0.02 Torr)
Dichte	1.166±0.06 g/cm3(Predicted)
Dampfdruck	0.004Pa at 25℃
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
pka	13.03±0.20(Predicted)
Farbe	White to Off-White
Wasserlöslichkeit	Soluble in water, ethanol, ether, chloroform, and propylene glycol.
Sensitive	Hygroscopic
Merck	14,2947
BRN	1724945
InChIKey	SNPLKNRPJHDVJA-UHFFFAOYSA-N
LogP	-1.02 at 22℃
CAS Datenbank	16485-10-2(CAS DataBase Reference)
EPA chemische Informationen	Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- (16485-10-2)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	36/37/38-48-41-37/38-20/21/22
S-Sätze:	26-37-45-36/37/39-22
WGK Germany	3
RTECS-Nr.	ES4316500
F	3
TSCA	Yes
HS Code	29362400
Toxizität	mouse,LD50,intraperitoneal,10100mg/kg (10100mg/kg),Farmaco, Edizione Scientifica. Vol. 14, Pg. 43, 1959.

Gefahreninformationscode (GHS)

Panthenol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R48:Gefahr ernster Gesundheitsschäden bei längerer Exposition.
R41:Gefahr ernster Augenschäden.
R37/38:Reizt die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37:Geeignete Schutzhandschuhe tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S22:Staub nicht einatmen.
Verwenden
vitamin B5 precursor, radioprotectant, antimalarial
Verwenden
DL-Panthenol is used in the topical treatment of skin disorders, such as minor irritations and skin burns. Also used in the strengthening and treatment of hair.
Verwenden
panthenol (pro-vitamin B5) acts as a penetrating moisturizer. Panthenol appears to stimulate cellular proliferation and aid in tissue repair. Studies indicate that when topically applied, panthenol penetrates the skin and gets converted into pantothenic acid, a B complex vitamin. Such action could possibly influence the skin’s natural resources of pantothenic acid. It imparts a nonirritant, non-sensitizing, moisturizing, and conditioning feel and promotes normal keratinization and wound-healing. Panthenol protects the skin against sunburn, provides relief for existing sunburn, and enhances the natural tanning process. Panthenol’s humectant character enables it to hold water in the product or attract water from the environment, resulting in a moisturizing effect. It enhances skin suppleness, and claims are that it also acts as an anti-inflammatory agent. It is considered a non-comedogenic raw material.
Allgemeine Beschreibung
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists in two optically active forms, both of which are used in pharmaceutical preparations. While pantothenic acid is optically active, only the dextrorotatory form is biologically active. Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.
Flammability and Explosibility
Non flammable

Panthenol , DL-Form Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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