5-Amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoesure

Bezeichnung:5-Amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoesure

CAS-Nr3326-34-9

Englisch Name:5-Aminofluorescein

CBNumberCB3254491

SummenformelC20H13NO5

Molgewicht347.32

MOL-Datei3326-34-9.mol

Synonyma

5-Amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoesure

5-Amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoesure physikalisch-chemischer Eigenschaften

Schmelzpunkt	223 °C (dec.)(lit.)
Siedepunkt	481.89°C (rough estimate)
Dichte	1.3724 (rough estimate)
Brechungsindex	1.5180 (estimate)
storage temp.	room temp
Löslichkeit	DMF: 5 mg/ml; DMSO: 5 mg/ml
Aggregatzustand	powder
pka	9.34±0.20(Predicted)
Farbe	red-brown
Wasserlöslichkeit	Soluble in water (partly), methanol (10 mg/ml), and acetone.
BRN	48395
Stabilität	Light and Moisture Sensitive
InChIKey	GZAJOEGTZDUSKS-UHFFFAOYSA-N
CAS Datenbank	3326-34-9(CAS DataBase Reference)
EPA chemische Informationen	Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5-amino-3',6'-dihydroxy- (3326-34-9)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-36/37/38
S-Sätze:	26
WGK Germany	3
F	10
TSCA	Yes
HS Code	32049090

Gefahreninformationscode (GHS)

5-Aminofluorescein Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Dark Red Solid
Verwenden
5-aminofluorescein is also used to prepare FITC Isomer I (CDX-F0011, CDX-F0020). It is a chemical used as molecular probe and important as fluorescent dye and for derivatives. Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens.
Verwenden
Glycosaminoglycuronans react with 5-aminofluorescein to yield fluorescent derivatives. 5-aminofluorescein is also used to prepare FITC Isomer I (F-011, F-020).
Definition
ChEBI: 5-aminofluorescein is a primary amino compound that is fluorescein carrying an amino substituent at C-5. Building block/intermediate for the synthesis of the fluorescent dye flourescein; also used to produce N-(fluorescein-5-yl)maleamic acid. It derives from a fluorescein (lactone form).
synthetische
The preparation of 5-aminofluorescein is carried out either by first saponification of 5-nitrofluorescein acetates with alcohol alkali, followed by reduction of the obtained 5-nitrofluorescein in a solution of alcohol alkali with hydrazine hydrate on a nickel catalyst to obtain 5-aminofluorescein , Or by boiling in an aqueous solution of sodium sulfide. The restoration of the nitro group and the saponification of acetates in the second case occurs in one stage.
Allgemeine Beschreibung
Fluoresceinamine, isomer I belongs to the class of derivatized fluoresceins.

5-Aminofluorescein Upstream-Materialien And Downstream Produkte

5-Amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoesure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

3326-34-9, 5-Aminofluorescein Verwandte Suche:

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