(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium

(16R)-17-Hydroxy-16-(methoxycarbonyl)-4α-methylsarpagan-4-ium Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  The bark of Strychnos toxifera yields three closely-related quaternary alkaloids, Macusines A, Band C. This particular base has been isolated as the crystalline chloride which forms clusters of prisms from EhOH-Et20, m.p. 252°C after sintering at 248°C; [α]²⁵_D - 57.5° (c 1.455, H20). The alkaloid also forms the iodide, best crystallized from aqueous MeOH, m.p. 274°C (dec.) and the picrate, m.p. 255°C (dec.). The l6-epimer of this base is Macusine C.

• Einzelnachweise

  Battersby et al., 1. Chern. Soc., 1848 (1960) McPhail et al., Proc. Chern. Soc., 223 (1961) McPhail, Robertson, Sim.,J. Chern. Soc., 1832 (1963) Battersby, Yeowell., ibid, 4419 (1964)