(2R,3R,5R,11S,22S)-3,11-Methanoaspidofractinin-22-ol

(2R,3R,5R,11S,22S)-3,11-Methanoaspidofractinin-22-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  An imidazolidinocarbazole alkaloid, this base occurs in Aspidosperma duckei Hub. and also in A. macrocarpon Mart. It may be purified by recrystallization from either MeOH or CHC1 3 when it forms colourless needles. It has [α]²⁷_D + 16.7° (c 0.6, CHC13 ). The ultraviolet spectrum in ethanol solution has absorp-tion maxima at 246 and 297 mil. In 5N/HCl the absorption maxima occur at 262 and 268.5 mil with shoulders at 249 and 255 mil. The alkaloid contains one hydroxyl group and on acetylation yields the O-acetate, m.p. 202-5°C; [α]²⁶_D + 37° (c 2.97, CHCI3 ).

• Einzelnachweise

  Filho et al., J. Chem. Soc., C, 1260 (1966)