Bifluranol

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Bifluranol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Definition

  ChEBI: (2S,3R)-bifluranol is a 4,4'-pentane-2,3-diylbis(2-fluorophenol) that has (2S,3R)-stereoconfiguration. It is an enantiomer of a (2R,3S)-bifluranol.

• Biologische Aktivität

  Bifluranol (BX341) has anti-androgenic activity.

• in vivo

  The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog. It is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [ ³ H]it to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of ³ H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat). , 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL ^-1 (rat) or 1 ng Bifluranol equivalents mL ^-1 (ferret).

Bifluranol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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