R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE

R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  R(+)-SKF-81297 Hydrobromide is a dopamine D1 agonist.

• Verwenden

  R(+)-SKF-81297 hydrobromide has used as D1-type dopamine receptor agonist:
  
  • to test it effect on the spike firing in rat retinal ganglion cells
  • in human embryonic kidney (HEK) 293T cells
  • to test its inhibitory effect in microglial cells
  
  

• Biochem/physiol Actions

  SKF-81297 administration in spontaneously hypertensive rats (SHR) induces an increase in expression of proto-oncogene c-fos mRNA leading to biphasic effect on locomotion. It favors the turnover of phosphoinositide and adenylyl cyclase. SKF-81297 is involved in the stimulation of neurons, in particular the postsynaptic striatal neurons.

R(+)-SKF-81297 HYDROBROMIDE SELECTIVE D1 DOPAMINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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