N,N-Dimethyl-N'-2-pyridinyl-N'-(3-thienylmethyl)-1,2-ethandiamin

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

• Sicherheit

  P264：Nach Gebrauch gründlich waschen.

  P264：Nach Gebrauch gründlich waschen.

  P270：Bei Gebrauch nicht essen, trinken oder rauchen.

  P301+P312：BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

  P330：Mund ausspülen.

  P501：Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

thenyldiamine Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Liquid.

• Originator

  Thenyldiamine,ZYF Pharm Chemical

• Verwenden

  Medicine (as base for various salts, especially the hydrochloride).

• Definition

  ChEBI: Thenyldiamine is a dialkylarylamine and a tertiary amino compound.

• Manufacturing Process

  To a suspension of 3.12 g of sodium amide in 50 ml dry toluene was added dropwise 12 g of 2-(dimethylamino)ethylaminopyridine. The mixture was refluxed for 2 hours, cooled to 50°C, and 21 g 3-thenyl bromide was added dropwise. When reaction subsided, the brownish-orange mixture was refluxed for 0.5 hour, cooled, and poured into 150 ml of water. The toluene layer was separated, extracted with 5% hydrochloric acid. This extract was saturated with potassium carbonate. The free base was extracted with ether, dried and fractionated. Yield of N,N-dimethyl-N'-2-pyridinyl-N'-(3-thienylmethyl)-1,2- ethanediamine 31%, boiling point 169-172°C/1 mm.
  106 g of the free base was dissolved in 500 ml of isopropyl alcohol and 34 ml concentrated hydrochloric acid was added. After shaking, the reaction mixture was allowed to added. After through cooling in an ice-methanol mixture, the salt was collected and washed on the filter with low boiling petroleum ether, Melting point of N,N-dimethyl-N'-2-pyridinyl-N'-(3-thienylmethyl)-1,2- ethanediamine hydrochloride 169.5-170°C.

• Therapeutic Function

  Antihistaminic

thenyldiamine Upstream-Materialien And Downstream Produkte

N,N-Dimethyl-N'-2-pyridinyl-N'-(3-thienylmethyl)-1,2-ethandiamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(14)Suppliers

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