5-Methylfuran-2(3H)-on

Bezeichnung:5-Methylfuran-2(3H)-on

CAS-Nr591-12-8

Englisch Name:alpha-Angelica lactone

CBNumberCB2760151

SummenformelC5H6O2

Molgewicht98.1

MOL-Datei591-12-8.mol

Synonyma

5-Methylfuran-2(3H)-on

5-Methylfuran-2(3H)-on physikalisch-chemischer Eigenschaften

Schmelzpunkt	13-17 °C(lit.)
Siedepunkt	55-56 °C12 mm Hg(lit.)
Dichte	1.092 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.448(lit.)
FEMA	3293 \| 4-HYDROXY-3-PENTENOIC ACID LACTONE
Flammpunkt	155 °F
storage temp.	2-8°C
Löslichkeit	Chloroform, Ethyl Acetate
Aggregatzustand	Oil
pka	pK1:4.3 (25°C)
Wichte	1.101.092
Farbe	Clear Light Yellow
Geruch (Odor)	at 10.00 % in dipropylene glycol. sweet solvent nutty tonka coumarin tobacco
Geruchsart	coconut
Wasserlöslichkeit	5 g/100 mL (25 ºC)
Merck	14,647
JECFA Number	221
BRN	108394
LogP	0.84
CAS Datenbank	591-12-8(CAS DataBase Reference)
NIST chemische Informationen	2(3H)-Furanone, 5-methyl-(591-12-8)
EPA chemische Informationen	5-Methyl-2(3H)-furanone (591-12-8)

Sicherheit

S-Sätze:	24/25
RIDADR	NA 1993 / PGIII
WGK Germany	2
RTECS-Nr.	LU5075000
F	10-21
TSCA	Yes
HS Code	29322090
Toxizität	LD50 orl-mus: 2800 mg/kg DCTODJ 3,249,80

Gefahreninformationscode (GHS)

alpha-Angelica lactone Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
α-Angelica lactone has a sweet, herbaceous odor reminiscent of tobacco.
Chemische Eigenschaften
clear colorless to straw yellow liquid
Occurrence
Reported found in grape, white bread, soy bean and licorice.
Verwenden
alpha-Angelicalactone acts as acancer chemopreventive agent. It is used in the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver. It is used in oral care formulations to round out mint notes and in coffee flavors.
synthetische
By dry distillation of levulinic acid
Application
alpha-Angelica lactone finds occasional use in the reconstitution of essential oils. lts intensely sweet-herbaceous, almost tobacco-like odor makes this chemical interesting for application in new fragrance types. However, it would be wise to investigate its pharmacological and dermatological properties first.
Definition
ChEBI: Alpha-angelica lactone is an angelica lactone and a butenolide. It is functionally related to a but-3-en-4-olide. It is a tautomer of a beta-angelica lactone.
Taste threshold values
Taste characteristics at 100 ppm: sweet, creamy, coconut, vanilla hay and coumarin-like nuances
Allgemeine Beschreibung
α-Angelica lactone, a cyclic lactone that occurs naturally in tobacco, is generally used in tobacco flavoring.
Biochem/physiol Actions
Plant-derived cancer chemopreventive agent. Increases the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver.
Sicherheitsprofil
Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits acrid smoke and irritating fumes.

alpha-Angelica lactone Upstream-Materialien And Downstream Produkte

5-Methylfuran-2(3H)-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

591-12-8, alpha-Angelica lactone Verwandte Suche:

Send Inquriy