Pyridin-4-thiol

Bezeichnung:Pyridin-4-thiol

CAS-Nr4556-23-4

Englisch Name:4-Mercaptopyridine

CBNumberCB2748207

SummenformelC5H5NS

Molgewicht111.16

MOL-Datei4556-23-4.mol

Synonyma

Pyridin-4-thiol

Pyridin-4-thiol physikalisch-chemischer Eigenschaften

Schmelzpunkt	182-189 °C
Siedepunkt	194.0±13.0 °C(Predicted)
Dichte	1.161 (estimate)
Brechungsindex	1.5605 (estimate)
storage temp.	2-8°C
Löslichkeit	DMSO, Methanol
pka	pK1:1.43(＋1);pK2:8.86(0) (20°C)
Aggregatzustand	Crystalline Powder
Farbe	Yellow to yellow-green or brown
InChIKey	FHTDDANQIMVWKZ-UHFFFAOYSA-N
CAS Datenbank	4556-23-4(CAS DataBase Reference)
NIST chemische Informationen	4-Pyridinethiol(4556-23-4)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-37/39-24/25
WGK Germany	3
RTECS-Nr.	UT8578000
HS Code	29333990

Gefahreninformationscode (GHS)

4-Mercaptopyridine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
4-Mercaptopyridine is Yellow to light yellow crystalline powder
Verwenden
4-Mercaptopyridine is a pyridine derivative used as a redox reagents for the in vitro refolding of a recombinantly expressed single-chain Fv fragment (scFvOx). Used in studies along with thiosulfate to measure alliinase activity.
Verwenden
4-Mercaptopyridine was used as a probe molecule to study the performance of the gold nanorod (AuNR)/polycaprolactone (PCL) fibrous mesh.
Verwenden
mercaptopyridine is also known as sodium pyrithione. It is a preservative that is not commoly used.
läuterung methode
Purify the thiol by dissolving ~45g in boiling H2O (100mL) (charcoal), filter and precipitate it by adding 50% aqueous NaOH (~80mL) to pH ~6. Dissolve the precipitate in EtOH, evaporate it to dryness, then crystallise it from boiling EtOH (~100mL, charcoal) to give yellow flat hexagonal plates (m 186o). It sublimes readily in vacuo. [King & Ware J Chem Soc 873 1939.] The picrate forms yellow needles from H2O with m 222o(dec). The 4-methylmercaptopyridine derivative crystallises from pet ether (m 47o , also 44-45o was reported, with a pK2 0 of 5.97) and was prepared by treatment with MeI/NaOH. Its picrate has m 2 4 5o (from H2O, MeOH or EtOH). The N-methyl-4-pyridinethiol derivative has m 168.5-170o (from EtOH), a pK2 0 of 1.30 and is soluble in CHCl3. [Albert & Barlin J Chem Soc 2384 1959, Beilstein 21 II 35, 22 III/IV 373, 22/7 V 147.]

4-Mercaptopyridine Upstream-Materialien And Downstream Produkte

Pyridin-4-thiol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

4556-23-4, 4-Mercaptopyridine Verwandte Suche:

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