5-Nitro-2-furaldehyd

Bezeichnung:5-Nitro-2-furaldehyd

CAS-Nr698-63-5

Englisch Name:5-Nitrofurfural

CBNumberCB2711562

SummenformelC5H3NO4

Molgewicht141.08

MOL-Datei698-63-5.mol

Synonyma

5-Nitro-2-furaldehyd

5-Nitro-2-furaldehyd physikalisch-chemischer Eigenschaften

Schmelzpunkt	37-39 °C(lit.)
Siedepunkt	121 °C10 mm Hg(lit.)
Dichte	1.349 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.59(lit.)
Flammpunkt	92 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
Aggregatzustand	Crystalline Low Melting Solid
Farbe	Yellow to brown
Wasserlöslichkeit	sparingly soluble
Sensitive	Air & Light Sensitive
BRN	120539
InChIKey	SXINBFXPADXIEY-UHFFFAOYSA-N
CAS Datenbank	698-63-5(CAS DataBase Reference)
NIST chemische Informationen	2-Furancarboxaldehyde, 5-nitro-(698-63-5)

Sicherheit

Kennzeichnung gefährlicher	F,Xi,Xn
R-Sätze:	11-68-10
S-Sätze:	16-36/37
RIDADR	UN 1325 4.1/PG 2
WGK Germany	3
RTECS-Nr.	LT7200000
Hazard Note	Irritant
HazardClass	3.2
PackingGroup	III
HS Code	29321900
Giftige Stoffe Daten	698-63-5(Hazardous Substances Data)

Gefahreninformationscode (GHS)

5-Nitrofurfural Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R68:Irreversibler Schaden möglich.
R10:Entzündlich.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
Nitrofuran carboxaldehyde (NFC) is used to synthesize many drugs and chemicals such as nifuraldezone, puraguanidine, nifuratrone, furmethoxadone, etc. Furfural the main structure of NFC was determined many years ago to be a byproduct of formic acid synthesis. Furfural is produced from agricultural byproducts such as sugarcane bagasse and corncobs.
Chemische Eigenschaften
Yellow to brown crystalline low melting solid
Verwenden
NFC and its derivatives have antibacterial and antifungal activities. They destroy both gram-positive and gram-negative organisms such as Staphylococcus aureus, Salmonella schotmuelleri, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Streptococcus pyogenes. They may be used as antibacterial agents in a prophylactic manner, for example, in cleaning and disinfecting products. This compound also has antitrichomonal and antifungal activities.
Verwenden
5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates.
Definition
ChEBI: 5-Nitrofurfural is a C-nitro compound and a member of furans.
Vorbereitung Methode
Furfural is nitrated in acetic anhydride solution at 25 – 40 ℃ to give the diacetate [92-55-7], which is purified by recrystallization from isopropanol and then used directly for the production of derived drugs.
Toxicity evaluation
NFC inhibits the uptake of oxygen and disrupts cellular respiration within mitochondria. NFC and other nitrofurans are relatively potent inhibitors of monoamine oxidase enzyme in mammalian and avian species.

5-Nitrofurfural Upstream-Materialien And Downstream Produkte

5-Nitro-2-furaldehyd Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

698-63-5, 5-Nitrofurfural Verwandte Suche:

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