ANTI-RYANODINE RECEPTOR

ANTI-RYANODINE RECEPTOR Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Anti-Ryanodine Receptor has been used in immunofluorescence assay.

• Allgemeine Beschreibung

  RyR1 (ryanodine receptor isoform 1) is a homotetrameric intracellular calcium channel, that is present in skeletal muscle tissue. It is located on human chromosome 19q13.1. In rats, RyR1 and RyR2 are expressed in PASMCs (pulmonary artery smooth muscle cells).

• Biochem/physiol Actions

  In rats PASMCs (pulmonary artery smooth muscle cells), RyR2 (ryanodine receptor isoform 1) participates in RyR-gated Ca2+ entry. It controls the secretion of insulin and glucose homeostasis. After hemorrhagic shock, RyR2 involves in the progress of vascular bi-phasic reactivity to NE (norepinephrine). In human, RyR1 plays an important role in muscle contraction. RYR1 mutation causes CCD (central core disease) and MHS (malignant hyperthermia susceptibility).

ANTI-RYANODINE RECEPTOR Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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