Erythromycinglucoheptonat

ERYTHROMYCIN GLUCEPTATE (200 MG) Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Ilotycin Gluceptate,Dista,US,1954

• Verwenden

  Erythromycin Glucoheptonate is a derivative of Erythromycin (E649950), an antibiotic.

• Verwenden

  Antibacterial.

• Manufacturing Process

  A solution of 10 grams of d-glucoheptonic acid lactone in 50 ml of distilled water is warmed on a steam bath for about 2 hours to hydrolyze the lactone to the acid. The mixture is cooled and 100 ml of 95% ethanol are added. To the solution of glucoheptonic acid are added about 37 grams of erythromycin and the volume of the reaction mixture is brought to 200 ml by the addition of 95% ethanol. The reaction mixture is stirred for about 2 hours and is filtered through a porcelain filter candle of porosity 02. To provide a sterile product, aseptic technique is used throughout the remainder of the procedure. To the filtered solution are added slowly and with stirring about 1,200 ml of anhydrous ether, to cause precipitation of erythromycin d-glucoheptonate and to keep in solution any excess of unreacted erythromycin. The precipitated erythromycin salt is removed by filtration through a sintered glass funnel, is washed with anhydrous ether and is dried in vacuo. Erythromycin dglucoheptonate melts over a range of about 95° to 140°C.

• Trademarks

  Ilotycin (Dista).

• Therapeutic Function

  Antibacterial

ERYTHROMYCIN GLUCEPTATE (200 MG) Upstream-Materialien And Downstream Produkte

Erythromycinglucoheptonat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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