Suprofen Produkt Beschreibung

Suprofen Struktur
40828-46-4
  • CAS-Nr.40828-46-4
  • Bezeichnung:Suprofen
  • Englisch Name:Suprofen
  • Synonyma:Suprofen
    r25061;Suprol;TN 762;Anemet;Srendam;maldocil;Suprocil;Topalgic;Profenal;Profenol
  • CBNumber:CB2496867
  • Summenformel:C14H12O3S
  • Molgewicht:260.30828
  • MOL-Datei:40828-46-4.mol
Suprofen physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :278°C
  • Siedepunkt: :373.57°C (rough estimate)
  • Dichte :1.2959 (rough estimate)
  • Brechungsindex :1.5050 (estimate)
  • storage temp.  :-20°C Freezer
  • pka :3.91(at 25℃)
  • Wasserlöslichkeit :soluble
  • CAS Datenbank :40828-46-4(CAS DataBase Reference)
Sicherheit
  • RIDADR  :3249
  • HazardClass  :6.1(b)
  • PackingGroup  :III
  • HS Code  :2934990002
  • Toxizität :LD50 (7 days post-drug) in mice, rats, guinea pigs, dogs (mg/kg): 590, 353, 280, 160 orally (Niemegeers)

Suprofen Chemische Eigenschaften,Einsatz,Produktion Methoden

  • Beschreibung Suprofen is an arylpropionic acid analgesic/antiinflammatory agent with close structural resemblance to ketoprofen. It is more potent in many assays than indomethacin and ketoprofen and appears better tolerated.
  • Chemische Eigenschaften Off-White to Light-Brown
  • Originator Janssen (Belgium)
  • Verwenden Prostaglandin biosynthesis inhibitor. Analgesic
  • Verwenden Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.
  • Definition ChEBI: An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
  • Trademarks Profenal (Alcon);Algiamida;Algiasdi;Bordol;Erdol;Masterfen;Sufenid;Supranol;Surfex;MALDOCIL.
  • Veterinary Drugs and Treatments Suprofen is a non-steroidal anti-inflammatory agent similar to flurbiprofen. Suprofen and flurbiprofen are phenylalkanoic acids that inhibit the cyclo-oxygenase enzymes responsible for conversion of arachadonic acid from cell membranes into various prostaglandins. These prostaglandins mediate certain aspects of ocular inflammation including disruption of the blood-aqueous barrier, uveal vasodilation, increases in intraocular pressure, and leakage of white blood cells and protein from uveal vessels into the aqueous humor. Prostaglandins cause iris sphincter constriction (miosis) independent of cholinergic mechanisms. Suprofen can inhibit this intraocular miosis and may also be useful in the management of uveal inflammation (usually in addition to topical steroids).
Suprofen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Suprofen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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40828-46-4, Suprofen Verwandte Suche:
  • 1H-Indole-3-carboxylic acid(2α,6α,8α,9αβ)-octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester
  • Dolasetron Methanesulformte
  • MDL-73147EF:Anzemet
  • 2-[4-(Thiophene-2-carbonyl)phenyl]propanoic acid
  • a-Methyl-p-(2-thenoyl)phenylacetic acid
  • 2-[4-(thiophene-2-carbonyl)phenyl]propionic acid
  • Suprofen (200 mg)
  • α-Methyl-4-(2-thienylcarbonyl)benzeneacetic Acid
  • para-(2-Thenoyl) hydratropic acid
  • Maldocil,Masterfen,Supranol,Supro,
  • (+-)-2-(p-(2-thenoyl)phenyl)propionicacid
  • alpha-methyl-4-(2-thienylcarbonyl)-benzeneaceticaci
  • alpha-methyl-4-(2-thienylcarbonyl)benzeneaceticacid
  • maldocil
  • p-(2-thenoyl)-hydratropicaci
  • p-(2-thenoyl)hydratropicacid
  • r25061
  • a-Methyl-4-(2-thienylcarbonyl)benzeneacetic Acid
  • Masterfen
  • Srendam
  • Sulprotin
  • Suprocil
  • Suprol
  • Sutoprofen
  • Topalgic
  • DOLASETRON(FREE BASE)
  • Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)- (9CI)
  • NSC 303611
  • Profenal
  • Profenol
  • Racemic suprofen
  • Sulproltin
  • TN 762
  • 2-(4-Thiophen-2-ylcarbonylphenyl)propanoic acid
  • Suprofen
  • BENZENEACETICACID,A-METHYL-4-(2-THIENYLCARBONYL)
  • Anemet
  • MDL 73147
  • Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl Ester 1H-Indole-3-carboxylic Acid Stereoisomer
  • 40828-46-4
  • 115956-12-0
  • 115952-12-2
  • Heterocyclic Compounds
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Inhibitors
  • -