Methylprednisolone aceponate Struktur

Methylprednisolone aceponate

Bezeichnung:Methylprednisolone aceponate

CAS-Nr86401-95-8

Englisch Name:Methylprednisolone aceponate

CBNumberCB2483146

SummenformelC27H36O7

Molgewicht472.57

MOL-Datei86401-95-8.mol

Methylprednisolone aceponate physikalisch-chemischer Eigenschaften

Schmelzpunkt	105 - 108°C
Siedepunkt	595.8±50.0 °C(Predicted)
Dichte	1.23±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Ethyl Acetate(Slightly)
Aggregatzustand	Solid
pka	14.05±0.70(Predicted)
Farbe	White to Off-White
InChIKey	DALKLAYLIPSCQL-TXWHWSFMNA-N
SMILES	O(C(CC)=O)[C@]1(C(COC(C)=O)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(C=C[C@]4(C)[C@H]3[C@H](C[C@]12C)O)=O \|&1:5,15,16,18,25,27,28,30,r\|

Gefahreninformationscode (GHS)

Methylprednisolone aceponate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Methylprednisolone aceponate (MPA) is a new potent topical corticosteroid. Chemically, it is a corticosteroid diester that penetrates the skin rapidly. It is rapidly metabolised and then conjugated, so although potent, it does not appear to cause serious local or systemic side effects. Clinical trials have shown that once daily use is sufficient to control most eczematous conditions and is also appropriate and effective in atopic dermatitis. MPA is effective in the treatment of facial and scalp eczema and sunburn and has shown promising results in the treatment of psoriasis. MPA is also suitable for use in children and infants. MPA is available in a wide range of formulations (0.1%) including creams, ointments, fat ointments, lotions and solutions depending on the patient's individual condition.
Verwenden
Methylprednisolone aceponate used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.
Definition
ChEBI: Methylprednisolone aceponate is a corticosteroid hormone.
Handelsname
ADVANTAN^?
Nebenwirkungen
The most common side effects of Methylprednisolone aceponate (MPA) include itching and burning sensation. Other rare side effects are skin infection at the application site, redness, swelling or irritation at the application site, skin infection or the appearance of small blood vessels on the surface, stretch marks, acne, infection of the hair follicles at the application site, excessive growth of unwanted hair, discolouration of the skin and allergic reactions. If any serious adverse reaction occurs, contact your doctor promptly.

Methylprednisolone aceponate Upstream-Materialien And Downstream Produkte

Methylprednisolone aceponate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

86401-95-8, Methylprednisolone aceponate Verwandte Suche:

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