GC 14

GC 14 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  GC 14 is a thyroid hormone antagonist.

  GC 14 contains extensions at the 5′-position of the outer thyronine ring or from the bridging carbon and has only a modest affinity and potency for the thyroid hormone receptor (TR) that limits studies of their antagonistic actions[2].

• Einzelnachweise

  [1]. Chiellini G, et al. Synthesis and biological activity of novel thyroid hormone analogues: 5'-aryl substituted GC-1 derivatives. Bioorg Med Chem. 2002 Feb;10(2):333-46. [2]. Nguyen NH, et al. Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment. J Med Chem. 2002 Jul 18;45(15):3310-20.

GC 14 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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