2-Amino-3-chlorbenzoesure

Bezeichnung:2-Amino-3-chlorbenzoesure

CAS-Nr6388-47-2

Englisch Name:2-Amino-3-chlorobenzoic acid

CBNumberCB2430094

SummenformelC7H6ClNO2

Molgewicht171.58

MOL-Datei6388-47-2.mol

Synonyma

2-Amino-3-chlorbenzoesure

2-Amino-3-chlorbenzoesure physikalisch-chemischer Eigenschaften

Schmelzpunkt	189-191 °C (lit.)
Siedepunkt	0°C
Dichte	1.476±0.06 g/cm3(Predicted)
Flammpunkt	0°C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	DMSO, Methanaol
Aggregatzustand	Solid
pka	4.57±0.10(Predicted)
Farbe	Yellow to brown
Wasserlöslichkeit	Soluble in water.
Sensitive	Air & Light Sensitive
InChI	InChI=1S/C7H6ClNO2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey	LWUAMROXVQLJKA-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=CC(Cl)=C1N
CAS Datenbank	6388-47-2(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-37/39-36
WGK Germany	1
Hazard Note	Irritant
HS Code	29224999

Gefahreninformationscode (GHS)

2-Amino-3-chlorobenzoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white to yellow, tan or grey crystalline powder
Verwenden
2-Amino-3-chlorobenzoic acid is used as pharmaceutical intermediates.
Verwenden
2-Amino-3-chlorobenzoic Acid is a plant growth regulator.
Synthesis Reference(s)
The Journal of Organic Chemistry, 17, p. 141, 1952 DOI: 10.1021/jo01135a014
Synthese
The synthesis of 2-Amino-3-chlorobenzoic acid is as follows:
70 ml of methanol was added to an autoclave, and cooled to -70° C., and 16 g (942 mmol) of a generated ammonia gas was added. 30 g (157 mmol) of 2,3-dichlorobenzoic acid and 0.78 g (7.85 mmol) of copper(I) chloride were added. The autoclave was sealed, and heated in an oil bath at 130° C. and 30 atmospheres for 20 hours. After the completion of the reaction, the autoclave was cooled to room temperature, and the reaction mixture was transferred into a reaction flask. 100 ml of water was added to the reaction solution, and the reaction solution was heated in an oil bath to 100° C. to remove the ammonia and the methanol. Then, the reaction solution was cooled to room temperature, and hydrochloric acid was added to adjust the pH value to 3. The precipitated crystals were filtered and dried to obtain 21.8 g of 2-amino-3-chlorobenzoic acid as white crystals with a yield of 81%.

2-Amino-3-chlorobenzoic acid Upstream-Materialien And Downstream Produkte

2-Amino-3-chlorbenzoesure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

6388-47-2, 2-Amino-3-chlorobenzoic acid Verwandte Suche:

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