Febuprol

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Febuprol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Valbil,Rohm Pharma,W. Germany,1981

• Definition

  ChEBI: Febuprol is an aromatic ether.

• Manufacturing Process

  Initially, 4.5 g (0.08 mol) pulverized potassium hydroxide was dissolved in 300 ml isopropanol in a 500 ml four-neck flask equipped with stirrer, intensive cooler, dropping funnel and feed pipe for the gas treatment with nitrogen.
  Then, 52.0 g (0.4 mol) n-butylglycidyl ether and 41.4 g (0.44 mol) phenol was added thereto, whereafter the material was heated to boiling under nitrogen. The material was stirred, about 8.5 hours, until no glycidyl ether could be determined, e.g., by gas chromatography.
  After the suspension was cooled under nitrogen, the solvent was distilled off under vacuum. The residue was taken up in 200 ml water and the milky emulsion extracted exhaustively with ether. From the organic phase, the excess butylglycidyl ether was extracted with diluted potassium hydroxide solution. The ether phase was washed neutral with water and the solvent removed after drying with sodium sulfate. The remaining oily residue was distilled under vacuum; there was obtained a colorless liquid of BP 123.5°C/0.07 mm. Yield: 81.8 g (91.1% of the theory)

• Therapeutic Function

  Choleretic

Febuprol Upstream-Materialien And Downstream Produkte

Febuprol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(36)Suppliers

3102-00-9, Febuprol Verwandte Suche: