Chinolin-4-ol

Bezeichnung:Chinolin-4-ol

CAS-Nr611-36-9

Englisch Name:4-Hydroxyquinoline

CBNumberCB2372460

SummenformelC9H7NO

Molgewicht145.16

MOL-Datei611-36-9.mol

Synonyma

Chinolin-4-ol

Chinolin-4-ol physikalisch-chemischer Eigenschaften

Schmelzpunkt	200-202 °C(lit.)
Siedepunkt	264.27°C (rough estimate)
Dichte	1.1555 (rough estimate)
Brechungsindex	1.4500 (estimate)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Soluble in methanol.
Aggregatzustand	Crystalline Powder or Needles
pka	2.23, 11.28(at 20℃)
Farbe	Light beige to yellow
Wasserlöslichkeit	4.8g/L(15 ºC)
BRN	1524969
InChIKey	PMZDQRJGMBOQBF-UHFFFAOYSA-N
LogP	2.450 (est)
CAS Datenbank	611-36-9(CAS DataBase Reference)
NIST chemische Informationen	4-Quinolinol(611-36-9)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-37/39
WGK Germany	3
RTECS-Nr.	VC4070000
HS Code	29334900

Gefahreninformationscode (GHS)

4-Hydroxyquinoline Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
4-Hydroxyquinoline is a quinoline alkaloid that has been found in Z. lotus honeys. It is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules such as 2-heptyl-3-hydroxy-4(1H)-quinolone and 2-nonyl-3-hydroxy-4-quinolone. 4-Hydroxyquinoline has been used as a precursor in the synthesis of compounds with antibacterial activity. It has also been used as a fluorescent detection reagent for iron(III) in bovine liver samples.
Chemische Eigenschaften
LIGHT BEIGE TO YELLOWISH CRYST. POWDER OR NEEDLES
Verwenden
4-Hydroxyquinolineis a hydroxylated quinoline derivative with antimicrobial activity. 4-Hydroxyquinoline showed growth-inhibitory effects against intestinal bacteria. 4-Hydroxyquinoline act as sacrifi cial scavengers of the photogenerated oxygen species and has been shown to prevent the photodegradation of riboflavin.
Verwenden
4-Hydroxyquinoline is a medical raw material.
Definition
ChEBI: A monohydroxyquinoline carrying a hydroxy group at position 4.
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1264, 1946 DOI: 10.1021/ja01211a038
Allgemeine Beschreibung
4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.
Biologische Aktivität
4-hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity. it shows growth-inhibitory effects against intestinal bacteria. it also can be used as sacrificial scavengers of the photogenerated oxygen species.

4-Hydroxyquinoline Upstream-Materialien And Downstream Produkte

Chinolin-4-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

611-36-9, 4-Hydroxyquinoline Verwandte Suche:

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