N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester)

N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester) Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  N-(Biotin-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

• Einzelnachweise

  [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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