Valeriansure

Bezeichnung:Valeriansure

CAS-Nr109-52-4

Englisch Name:Valeric acid

CBNumberCB2309387

SummenformelC5H10O2

Molgewicht102.13

MOL-Datei109-52-4.mol

Synonyma

Valeriansure

Pentans?ure

Propylessigs?ure

Valeriansure physikalisch-chemischer Eigenschaften

Schmelzpunkt	−20-−18 °C(lit.)
Siedepunkt	110-111 °C10 mm Hg(lit.)
Dichte	0.939 g/mL at 25 °C(lit.)
Dampfdichte	3.5 (vs air)
Dampfdruck	0.15 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.408(lit.)
FEMA	3101 \| VALERIC ACID
Flammpunkt	192 °F
storage temp.	Store below +30°C.
Löslichkeit	40g/l
Aggregatzustand	Liquid
pka	4.84(at 25℃)
Farbe	Clear colorless to pale yellow
PH	3.95(1 mM solution);3.43(10 mM solution);2.92(100 mM solution);
Geruch (Odor)	at 1.00 % in propylene glycol. sickening putrid acidic sweaty rancid
Geruchsart	cheesy
Odor Threshold	0.000037ppm
Explosionsgrenze	1.8-7.3%(V)
Wasserlöslichkeit	40 g/L (20 ºC)
Merck	14,9904
JECFA Number	90
BRN	969454
Dielectric constant	2.7（20℃）
LogP	1.8 at 25℃
CAS Datenbank	109-52-4(CAS DataBase Reference)
NIST chemische Informationen	Pentanoic acid(109-52-4)
EPA chemische Informationen	Valeric acid (109-52-4)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	34-52/53
S-Sätze:	26-36-45-61
RIDADR	UN 3265 8/PG 3
WGK Germany	1
RTECS-Nr.	YV6100000
F	13
Selbstentzündungstemperatur	707 °F
TSCA	Yes
HazardClass	8
PackingGroup	III
HS Code	29156090
Giftige Stoffe Daten	109-52-4(Hazardous Substances Data)
Toxizität	LD50 i.v. in mice: 1290 ±53 mg/kg (Or, Wretlind)

Gefahreninformationscode (GHS)

Valeric acid Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die Dämpfe sind schwerer als Luft.
CHEMISCHE GEFAHREN
Schwache Säure.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz verätzt die Augen, die Haut und die Atemwege. ätzend beim Verschlucken.
LECKAGE
Ausgelaufene Flüssigkeit in abgedeckten Behältern sammeln. Verschüttete Flüssigkeit mit viel Wasser wegspülen. NICHT in die Umwelt gelangen lassen.
R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
R52/53:Schädlich für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Valeric acid, or pentanoic acid, is a straight - chain alkyl carboxylic acid with the chemical formula C₅H₁₀O₂. Like other lowmolecular- weight carboxylic acids, it has a very unpleasant odor. It is found naturally in the perennial flowering plant valerian (Valeriana officinalis), from which it gets its name. Its primary use is in the synthesis of its esters. Volatile esters of valeric acid tend to have pleasant odors and are used in perfumes and cosmetics. Ethyl valerate and pentyl valerate are used as food additives because of their fruity flavors.
Valeric acid appears similar in structure to GHB and the neurotransmitter GABA in that it is a short-chain carboxylic acid, although it lacks the alcohol and amine functional groups that contribute to the biological activities of GHB and GABA, respectively. It differs from valproic acid simply by lacking a 3- carbon side - chain.
Chemische Eigenschaften
Colorless liquid; penetrating odor and taste. Soluble in water, alcohol and ether. Undergoes reactions typical of normal monobasic organic acids. Combustible.
Chemische Eigenschaften
Valeric acid has an unpleasant odor and flavor, similar to butyric acid. May consist of one or a mixture of isomers of n-pentanoic acid and/or 2- or 3-methyl-butanoic acid.
Occurrence
The acid is not too common in nature; reported (as the corresponding ester) found in the essential oil of Boronia anemonifolia, in pineapple fruits and in other plants; also identified as acid or the corresponding ester in the essential oil of lemon petitgrain. Also reported found in apple, apple juice, banana, orange juice, bilberry, cranberry, strawberry, raspberry, papaya, grapes, celery, onion, baked potato, tomato, corn mint oil, breads, cheeses, milk, yogurt, butter, cheddar cheese, lean and fatty fish, fish oil, cooked meats, hop oil, beer, rum, whiskies, grape wines, cocoa, tea, roasted filberts, peanuts and pecans, honey, soybeans, coconut meat and milk, cloudberry, passion fruit, starfruit, trassi, mango, jackfruit, licorice, calamus, sake, buckwheat, watercress, laurel, peated malt, wort, kiwifruit, loquat, Bourbon vanilla, shrimps, oyster, scallop, cape gooseberry, sea buckthorn, Chinese quince and maté.
Verwenden
valeric acid is obtained from valerian extract, which is considered skin conditioning.
Verwenden
Sex attractant of the sugar beet wireworm, Limonius californicus.1
Verwenden
Valeric acid, is used as a sex attractant of the sugar beet wireworm, Limonius californicus. It is used predominantly as an intermediate in the manufacture of flavors and perfumes, ester type lubricants, plasticizers and vinyl stabilizesrs. It is a food additive used as a synthetic flavoring substance dan adjuvant. It is an inert ingredient in controlling pest.
synthetische
By oxidation of n-amyl alcohol or, together with other isomers, by distillation of valerian roots; also by reacting butyl bromide and sodium cyanide with subsequent saponification of the formed butyl nitrile.
Definition
ChEBI: A straight-chain saturated fatty acid containing five carbon atoms.
Aroma threshold values
Detection: 940 ppb to 3 ppm
Taste threshold values
Taste characteristics at 100 ppm: acidic, dairy-like with milky and cheese nuances.
Synthesis Reference(s)
Synthetic Communications, 26, p. 165, 1996 DOI: 10.1080/00397919608003877
Tetrahedron Letters, 31, p. 1257, 1990 DOI: 10.1016/S0040-4039(00)88779-1
Tetrahedron, 40, p. 3635, 1984 DOI: 10.1016/S0040-4020(01)88794-9
Allgemeine Beschreibung
A colorless liquid with a penetrating unpleasant odor. Density 0.94 g / cm3. Freezing point -93.2°F (-34°C). Boiling point 365.7°F (185.4°C). Flash point 192°F (88.9°F). Corrosive to metals and tissue.
Air & Water Reaktionen
Water soluble.
Reaktivität anzeigen
Valeric acid is a carboxylic acid. Exothermically neutralizes bases, both organic and inorganic, producing water and a salt. Can react with active metals to form gaseous hydrogen and a metal salt. Reacts with cyanide salts to generate gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by reaction with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Reacts with sulfites, nitrites, thiosulfates and dithionites to generate flammable and/or toxic gases and heat. Reacts with carbonates and bicarbonates to generate a harmless gas (carbon dioxide) but still heat. Can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. May initiate polymerization reactions. May catalyze (increase the rate of) chemical reactions.
Health Hazard
Corrosive. Very destructive to tissues of the mucous membranes, upper respiratory tract, eyes, and skin. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, nausea and vomiting. Extremely destructive to skin. May be absorbed through the skin.
Brandgefahr
Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire.
Flammability and Explosibility
Non flammable
Sicherheitsprofil
Moderately toxic by ingestion, intravenous, and subcutaneous routes. Mildly toxic by inhalation. A corrosive irritant to skin, eyes, and mucous membranes. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. Used in perfumes.
läuterung methode
Water is removed from the acid by distillation using a Vigreux column (p 11), until the boiling point reaches 183o. A few crystals of KMnO4 are added, and after refluxing, the distillation is continued. [Andrews & Keefer J Am Chem Soc 83 3708 1961, Beilstein 2 H 299, 2 I 130, 2 II 263, 2 III 663, 2 IV 868.]

Valeric acid Upstream-Materialien And Downstream Produkte

Valeriansure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

109-52-4, Valeric acid Verwandte Suche:

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