3,3'-(1,3-Dioxo-1,3-digermoxandiyl)dipropionsure

Bezeichnung:3,3'-(1,3-Dioxo-1,3-digermoxandiyl)dipropionsure

CAS-Nr12758-40-6

Englisch Name:Carboxyethylgermanium sesquioxide

CBNumberCB2271237

SummenformelC6H10Ge2O7

Molgewicht339.37

MOL-Datei12758-40-6.mol

Synonyma

3,3'-(1,3-Dioxo-1,3-digermoxandiyl)dipropionsure

3,3'-(1,3-Dioxo-1,3-digermoxandiyl)dipropionsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	320°C
storage temp.	-20°C Freezer, Under inert atmosphere
Löslichkeit	Aqueous Base (Sparingly)
pka	3.6(at 25℃)
Aggregatzustand	Solid
Farbe	White to Off-White
Wichte	1.280
Geruch (Odor)	wh. odorless powd.
Wasserlöslichkeit	Slightly soluble in water.
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions
Merck	14,7795
InChIKey	XEABSBMNTNXEJM-UHFFFAOYSA-N
CAS Datenbank	12758-40-6(CAS DataBase Reference)
EPA chemische Informationen	2-(Carboxyethyl)germanium sesquioxide (12758-40-6)

Sicherheit

R-Sätze:	36/37/38
S-Sätze:	26-36/37/39
WGK Germany	2
RTECS-Nr.	UA2459750
TSCA	Yes
HS Code	2931.90.9051
Toxizität	LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz)

Gefahreninformationscode (GHS)

Carboxyethylgermanium sesquioxide Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium also exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Propagermanium has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.
Originator
Sanwa Kagaku (Japan)
Verwenden
antifungal and antiseptic
Verwenden
Bis(2-carboxyethylgermanium(IV) sesquioxide) can be used as a precursor in the preparation of photoluminescent carbon dots, applicable as fluorescent probes in bioimaging applications.
Verwenden
A bifunctional metalloligand with metal-C (Ge-C) bonds,bis(carboxyethylgermanium) sesquioxide, has been used to make two metal-organometallic frameworks (MOMFs). bis-(carboxyethylgermanium)sesquioxide is a as a promising anti-oxidative agent. Bis(carboxyethylgermanium) sesquioxide induce INF-γ and has undergone clinical trials with promising preclinical results.
Definition
ChEBI: Propagermanium is an organogermanium compound.
Trademarks
Serosion
Allgemeine Beschreibung
Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics.
Sicherheitsprofil
Moderately toxic by intravenous route. Experimental reproductive effects. See also GERMANIUM COMPOUNDS.

3,3'-(1,3-Dioxo-1,3-digermoxandiyl)dipropionsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

12758-40-6, Carboxyethylgermanium sesquioxide Verwandte Suche:

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