3,3'-Dithiobis[6-nitrobenzoe]sure

Bezeichnung:3,3'-Dithiobis[6-nitrobenzoe]sure

CAS-Nr69-78-3

Englisch Name:5,5′-Dithiobis(2-nitrobenzoic acid)

CBNumberCB2215444

SummenformelC14H8N2O8S2

Molgewicht396.35

MOL-Datei69-78-3.mol

Synonyma

3,3'-Dithiobis[6-nitrobenzoe]sure

3,3'-Dithiobis[6-nitrobenzoe]sure physikalisch-chemischer Eigenschaften

Schmelzpunkt	240-245 °C (dec.)(lit.)
Siedepunkt	671.9±55.0 °C(Predicted)
Dichte	1.67
Brechungsindex	1.6900 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	1.57±0.25(Predicted)
Aggregatzustand	Yellow solid
Farbe	Pale Yellow to Light Yellow
Wasserlöslichkeit	Soluble in water and ethanol.
Merck	14,3551
BRN	1896821
Stabilität	Stable. Incompatible with strong bases, strong oxidizing agents.
InChIKey	KIUMMUBSPKGMOY-UHFFFAOYSA-N
CAS Datenbank	69-78-3(CAS DataBase Reference)
EPA chemische Informationen	Benzoic acid, 3,3'-dithiobis[6-nitro- (69-78-3)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
RTECS-Nr.	DG9650000
F	10
TSCA	Yes
HS Code	29309070

Gefahreninformationscode (GHS)

5,5′-Dithiobis(2-nitrobenzoic acid) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Crystalline
Verwenden
Reagent for determination of sufhydryl groups.5,5'-dithiobis-(2-nitrobenzoic acid) is widely utilized as a non-fluorescent probe to quantify the number or the concentration of thiol groups in a sample. It acts as a cleavable cross-linking agent. It finds an important application as a sensitive reagent for determining free sulfhydryl content in proteins, peptides, and tissues. It is also employed in high-performance liquid chromatography (HPLC) to determine the alkylthiol content.
Verwenden
5,5′-Dithiobis(2-nitrobenzoic acid) is a water soluble reagent mainly used for the derivatization of sulfhydryl groups.
Verwenden
5,5′-Dithiobis(2-nitrobenzoic acid) is an membrane-impermeant thiol/disulfide exchange blocker. It is also used to quantify the number or concentration of thiol groups in a sample.
Definition
ChEBI: An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups.
Allgemeine Beschreibung
5,5′-Dithiobis(2-nitrobenzoic acid) is also called DTNB or Ellman′s reagent. It is a water soluble reagent, which interacts with thiol groups, and can be used conveniently at neutral pH. Thiolate anion (RS^-) reacts with Ellman′s reagent (DTNB^2-), to produce 2-nitro-5-thiobenzoate anion (TNB^2-) and one mixed disulfide (R-S-TNB^-). TNB^2- has a high molar absorption coefficient, and absorbs at 412nm. This absorption is independent of pH, at pH> 7.3.

3,3'-Dithiobis[6-nitrobenzoe]sure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

69-78-3, 5,5′-Dithiobis(2-nitrobenzoic acid) Verwandte Suche:

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