TETRODOTOXIN CITRATE
Bezeichnung:TETRODOTOXIN CITRATE
CAS-Nr18660-81-6
Englisch Name:TETRODOTOXIN CITRATE
CBNumberCB2192024
SummenformelC17H25N3O15
Molgewicht511.39
MOL-Datei18660-81-6.mol
TETRODOTOXIN CITRATE physikalisch-chemischer Eigenschaften
| storage temp. | Desiccate at -20°C |
| Löslichkeit | Citrate Buffer (pH 4.8): 30 mg/ml (100 mM) |
| Aggregatzustand | A solid |
| pka | 8.76(at 25℃) |
| Wasserlöslichkeit | Soluble to 100 mM in water |
| Stabilität | Unstable in Acidic solution, Unstable In Acidic Solution |
| Kennzeichnung gefährlicher | T+ |
| R-Sätze: | 26/27/28 |
| S-Sätze: | 22-36/37/39-45 |
| RTECS-Nr. | IO1450000 |
| Toxizität | A toxin contained in the ovary and liver of puffer fish, in the eggs of the California newt and in some other animals. It is used as a chemical tool for the study of ion channels. The s.c. LD50 in mice is 10 mg/kg. It is a toxicant of nerve and muscle by blocking sodium channels, this action causing nerve and muscle paralysis. Symptoms include weakening of voluntary muscles, respiratory failure from paralysis of the diaphragm and hypotension. There is no antidote. Therapy involves artificial respiration. |
