5-Chloro-1-indanone

Bezeichnung:5-Chloro-1-indanone

CAS-Nr42348-86-7

Englisch Name:5-Chloro-1-indanone

CBNumberCB2148511

SummenformelC9H7ClO

Molgewicht166.6

MOL-Datei42348-86-7.mol

5-Chloro-1-indanone physikalisch-chemischer Eigenschaften

Schmelzpunkt	94-98 °C (lit.)
Siedepunkt	124-125 °C (3 mmHg)
Dichte	1.1466 (rough estimate)
Brechungsindex	1.6000 (estimate)
Flammpunkt	124-125°C/3mm
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly)
Aggregatzustand	Solid
Farbe	Light Beige to Beige
Wasserlöslichkeit	insoluble
BRN	1448000
InChIKey	MEDSHTHCZIOVPU-UHFFFAOYSA-N
CAS Datenbank	42348-86-7(CAS DataBase Reference)
NIST chemische Informationen	5-Chloro-1-indanone(42348-86-7)
EPA chemische Informationen	1H-Inden-1-one, 5-chloro-2,3-dihydro- (42348-86-7)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	20/21/22-36/37/38
S-Sätze:	26-36
WGK Germany	3
Hazard Note	Irritant
TSCA	Yes
HS Code	29339900

Gefahreninformationscode (GHS)

5-Chloro-1-indanone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White Crystal
Verwenden
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.
Verwenden
5-Chloro-1-indanone is the important intermediate of du pont company's new varieties of pesticides indoxacarb (popular name: indoxacarb), is also a kind of important medicine intermediate simultaneously.
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors.
synthetische
3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃.
Synthetic method of 5-chloro-1-indanone
Allgemeine Beschreibung
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.

5-Chloro-1-indanone Upstream-Materialien And Downstream Produkte

5-Chloro-1-indanone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

42348-86-7, 5-Chloro-1-indanone Verwandte Suche:

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