saikogenin A

saikogenin A Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  Saikogenin A, extracted from the traditional Chinese medicine Bupleurum, is a dipeptidyl peptidase IV (DPP-IV) inhibitor.

• Biochem/physiol Actions

  Saikogenin A is a naturally occurring plant extract that has been shown to have a variety of biological activities. saikogenin A has anti-inflammatory and tumour cell growth inhibiting effects. Its anti-inflammatory effect is due to an increase in corticosterone caused by the release of ACTH and has a direct effect on the inflammatory process. It also inhibits the absorption of ultraviolet light by human skin cells and erythromycin-induced UvB damage.

• in vitro

  Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide.

• in vivo

  Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. It is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema . The anti-inflammatory action of it are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation.

• target

  DPP-IV

saikogenin A Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(30)Suppliers