DL-Hexan-1,2-diol

Bezeichnung:DL-Hexan-1,2-diol

CAS-Nr6920-22-5

Englisch Name:1,2-Hexanediol

CBNumberCB2119791

SummenformelC6H14O2

Molgewicht118.17

MOL-Datei6920-22-5.mol

Synonyma

DL-Hexan-1,2-diol

DL-Hexan-1,2-diol physikalisch-chemischer Eigenschaften

Schmelzpunkt	45°C
alpha	[α]D20 -0.3～+0.3゜ (neat)
Siedepunkt	223-224 °C (lit.)
Dichte	0.951 g/mL at 25 °C (lit.)
Dampfdruck	0.576Pa at 25℃
Brechungsindex	n20/D 1.442(lit.)
Flammpunkt	>230 °F
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
pka	14.49±0.20(Predicted)
Aggregatzustand	Liquid
Wichte	0.951
Farbe	Clear colorless to light yellow
Geruch (Odor)	at 100.00?%. bland
Wasserlöslichkeit	Miscible with water, lower aliphatic hydrocarbons and fatty acids.
Sensitive	Hygroscopic
BRN	1719244
InChIKey	FHKSXSQHXQEMOK-UHFFFAOYSA-N
LogP	0.58 at 25℃
CAS Datenbank	6920-22-5(CAS DataBase Reference)
EPA chemische Informationen	1,2-Hexanediol (6920-22-5)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-37/39
WGK Germany	2
F	3
TSCA	Yes
HS Code	29053990

Gefahreninformationscode (GHS)

1,2-Hexanediol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
1,2-Hexanediol is a linear aliphatic diol with a carbon chain length containing six carbons. It is a synthetic preservative and moisture-binding agent belonging to a class of agents known as higher molecular glycols. It is considered non-sensitizing. It is ideal for use as an emollient, humectant, and wetting agent in cosmetic and skin care products.
Chemische Eigenschaften
clear colorless to light yellow liquid.
Verwenden
DL-1,2-Hexanediol is a solvent used to dissolve other compounds in a formulation. It can be used in the ruthenium-catalyzed synthesis of oxazolidin-2-ones from urea. It can undergo ruthenium-hydride catalyzed dehydrative coupling with anilines to form substituted indole and quinoline products.
Application
In skin care: 1,2-Hexanediol is one of the most multi-functional ingredients in the cosmetic industry. It is used in skin care, hair care as well as beauty products. It is a great emollient as well as a humectant, that is, it preserves hydration on the skin while also softening it.
synthetische
1,2-Hexanediol was synthesized with an overall yield of approximately 45% using a multi-step process that involved a-bromination of caproic acid, followed by hydrolysis to a-hydroxycaproic acid, and concluded with reduction using lithium aluminum hydride. In an alternate method, the organic acid was oxidized with H2O2 to form a peroxy acid, which in turn epoxidized the olefin double bond and ultimately underwent hydrolysis to yield 1,2-hexanediol.
SYNTHESIS OF SOME HEXANEDIOLS
benefits
1,2 hexanediol is most commonly used as a solvent in skincare formulation. It pulls the moisture up from the deeper levels of the skin, as well as from the air, to help keep the top layers of your skin from drying out. This makes It very effective at keeping your skin hydrated and providing long-term moisture. It can also help to disperse pigments more evenly in makeup products and boost the antimicrobial activity of preservatives.
Allgemeine Beschreibung
1,2-Hexanediol acts as cosurfactant, used for modifying the sodium dodecyl sulfate micelles. Solubility of 1,2-hexanediol in supercritical CO₂has been reported. It has a tendency of self-association to form micelle-like aggregates.
Sicherheit(Safety)
1,2-Hexanediol is safe for skin and hair when used in lower concentrations. In an in-use safety evaluation for skin irritation and sensitization potential, 28 participants (males and females) were instructed to use a body wash containing 0.15% 1,2- hexanediol for a minimum of 3 times per week over a 30-day period. There was no evidence of erythema, edema, or dryness of application sites in any of the participants, and it was concluded that the product did not demonstrate a potential for eliciting skin irritation or sensitization.
Safety Assessment of 1,2-Glycols as Used in Cosmetics
läuterung methode
Fractionally distil it, preferably in a vacuum. Alternatively, dissolve it in Et2O, dry with K2CO3 then Na2SO4, filter, evaporate and distil it in a vacuum. The bis-4-nitrobenzoyl derivative has m 101.5-102.5o. [Rudloff Can J Chem 36 486 1958, Beilstein 1 I 251, 1 III 2200, 1 IV 2554.]

1,2-Hexanediol Upstream-Materialien And Downstream Produkte

DL-Hexan-1,2-diol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

6920-22-5, 1,2-Hexanediol Verwandte Suche:

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