CASPASE-3

CASPASE-3 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Caspase 3 human has been used to digest human r-vimentin. It has also been used in caspase-3 inhibition assay and protease inhibition assay.

• Allgemeine Beschreibung

  Human recombinant C-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kDa and 13.5 kDa subunits; the 13.5 kDa subunit contains the histidine tag.

• Biochem/physiol Actions

  Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase?3 is considered to be an effector caspase, activating pro-caspase?6 and pro-caspase?9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B.

CASPASE-3 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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