SODIUM CARBONATE, MONOHYDRATE

Bezeichnung:SODIUM CARBONATE, MONOHYDRATE

CAS-Nr5968-11-6

Englisch Name:SODIUM CARBONATE, MONOHYDRATE

CBNumberCB1704053

SummenformelCH5NaO4

Molgewicht104.04

MOL-Datei5968-11-6.mol

SODIUM CARBONATE, MONOHYDRATE physikalisch-chemischer Eigenschaften

Schmelzpunkt	851 °C(lit.)
Siedepunkt	1600 °C
Dichte	2.53
storage temp.	Store at RT.
Löslichkeit	H₂O: 1 M at 20 °C, clear, colorless
Aggregatzustand	Powder/Solid
Wichte	2.25
Farbe	White
Wasserlöslichkeit	Soluble in water. Insoluble in alcoholSoluble in water and glycerol. Insoluble in alcohol, acetone, alkyl acetates,benzonitrile and liquid ammonia.
Sensitive	Hygroscopic
Merck	14,8596
Dielectric constant	3.0（Ambient）
Stabilität	Stable. Incompatible with strong acids, aluminium, fluorine, lithium, phosphorus oxides.
LogP	-0.809 (est)
CAS Datenbank	5968-11-6(CAS DataBase Reference)
EPA chemische Informationen	Sodium carbonate, monohydrate (5968-11-6)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36
S-Sätze:	26-22
WGK Germany	1
RTECS-Nr.	VZ4050000
F	3
TSCA	Yes
HS Code	28362000

Gefahreninformationscode (GHS)

SODIUM CARBONATE, MONOHYDRATE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36:Reizt die Augen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Sodium carbonate is a white, almost white, or colorless inorganic salt, produced as crystalline powder or granules. It is hygroscopic and odorless with an alkaline taste.
Chemische Eigenschaften
white powder
Verwenden
Buffer component, may be used for the removal of peripheral membrane proteins.
Verwenden
Buffers; pH adjustment.
Verwenden
Sodium Carbonate Monohydrate can be used for sterilization or virus inactivating agent composition.
Vorbereitung Methode
Sodium carbonate is produced by the ammonia-soda process, also known as the Solvay process.
Pharmazeutische Anwendungen
Sodium carbonate is used as an alkalizing agent in injectable, ophthalmic, oral, and rectal formulations. In effervescent tablets or granules, sodium carbonate is used in combination with an acid, typically citric acid or tartaric acid. When the tablets or granules come into contact with water, an acid– base reaction occurs in which carbon dioxide gas is produced and the product disintegrates. Raw materials with low moisture contents are required to prevent the early triggering of the effervescent reaction.
As an alkalizing agent, concentrations of sodium carbonate between 2% and 5% w/w are used in compressed tablet formulations. As an effervescent agent, concentrations of sodium carbonate up to 10% w/w can be used.
Therapeutically, sodium carbonate is also used as an oral antacid.
Industrielle Verwendung
The most prominent characteristic of soda ash in solution is the high buffered pH response. For example, changing the sodium carbonate dosage from 0.03% to 30% only causes the solution pH to change from 10.5 to 11.7. Because of this, in mineral processing application, soda ash is used for pH control to a maximum value of 10.5.
Industrielle Verwendung
Soda ash is the name of various grades of sodium carbonate (Na2CO3). A large portion of soda ash is manufactured via the Solvay process, based on the following reaction:
NH₃+ CO₂ + H₂O → NH₄HCO₃
NaCl + NH₄HCO₃→ NaHCO₃ + NH₄Cl
2NaHCO₃ + heat → Na₂CO₃ + CO₂ (recycled)
Soda ash is an off-white to white anhydrous powder or granular material. The quality of soda ash is usually characterized by the percent of sodium oxide (Na₂O) content.
Sicherheit(Safety)
Sodium carbonate is used in injectable, oral, and rectal pharmaceutical formulations. The pure form of sodium carbonate is mildly toxic by ingestion, moderately toxic by inhalation and SC routes, and very toxic by the IP route. It is irritating to the skin and eyes. Dust and vapors of sodium carbonate may irritate mucous membranes, causing coughing and shortness of breath. It also has experimental reproductive effects.
Sodium carbonate can migrate to food from packaging materials. When used as an excipient or antacid, sodium carbonate is generally regarded as a nontoxic and nonirritating material.
LD50 (mouse, IP): 0.12 g/kg
LD50 (mouse, SC): 2.21 g/kg
LD50 (rat, oral): 4.09 g/kg
Lager
Sodium carbonate converts to the monohydrate form when in contact with water and produces heat. It begins to lose carbon dioxide at temperatures above 400℃ and decomposes before boiling. Store in airtight containers.
Inkompatibilitäten
Sodium carbonate decomposes when in contact with acids in the presence of water to produce carbon dioxide and effervescence. It may react violently with aluminum, phosphorous pentoxide, sulfuric acid, fluorine, and lithium.
Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections; ophthalmic solution; oral capsules and tablets; rectal suspensions). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in parenteral (powder for solution for injection) and nonparenteral medicines (oral effervescent tablets, soluble tablets, granules, lozenges, chewing gums) licensed in the UK.
USP32–NF27 allows either the anhydrous or the monohydrate form.

SODIUM CARBONATE, MONOHYDRATE Upstream-Materialien And Downstream Produkte

SODIUM CARBONATE, MONOHYDRATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

5968-11-6, SODIUM CARBONATE, MONOHYDRATE Verwandte Suche:

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