Phenyldichlorphosphat

Bezeichnung:Phenyldichlorphosphat

CAS-Nr770-12-7

Englisch Name:Phenyl dichlorophosphate

CBNumberCB1669062

SummenformelC6H5Cl2O2P

Molgewicht210.98

MOL-Datei770-12-7.mol

Synonyma

Phenyldichlorphosphat

Phenyldichlorphosphat physikalisch-chemischer Eigenschaften

Schmelzpunkt	-1 °C
Siedepunkt	241-243 °C (lit.)
Dichte	1.412 g/mL at 25 °C (lit.)
Dampfdruck	2.33Pa at 25℃
Brechungsindex	n20/D 1.523(lit.)
Flammpunkt	>230 °F
storage temp.	2-8°C
Löslichkeit	soluble in Chloroform
Aggregatzustand	Liquid
Farbe	Clear colorless to very slightly brown
Wasserlöslichkeit	Decomposes
Sensitive	Moisture Sensitive
Merck	14,7282
BRN	511863
Stabilität	Moisture Sensitive
InChIKey	TXFOLHZMICYNRM-UHFFFAOYSA-N
CAS Datenbank	770-12-7(CAS DataBase Reference)
NIST chemische Informationen	Phosphorodichloridic acid, phenyl ester(770-12-7)
EPA chemische Informationen	Phosphorodichloridic acid, phenyl ester (770-12-7)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	34-37
S-Sätze:	26-36/37/39-45
RIDADR	UN 3265 8/PG 2
WGK Germany	3
RTECS-Nr.	TD4393000
F	10
TSCA	Yes
HazardClass	8
PackingGroup	II
HS Code	29209085

Gefahreninformationscode (GHS)

Phenyl dichlorophosphate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
R37:Reizt die Atmungsorgane.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
clear colourless to very slightly brown liquid
Verwenden
Reagent for the preparation of phosphate diesters.
Verwenden
Reagent for preparation of phosphate diesters. Phenyl dichlorophosphate is used in the preparation of symmetrical phosphate diesters. It is used as a phosphorylating agent for alcohols and amines. It is also involved in the preparation of phenylphosphoro di-(1-imidazolidate) and 2-phenyl-bis-triazoloylphosphate, which is used in peptide synthesis. It plays a vital role in the Pfitzner-Moffatt oxidation which involves oxidation of alcohols to the corresponding aldehydes and ketones. Furthermore, it is utilized in Beckmann rearrangement for the preparation of N-phenylacetamide from acetophenone oxime.
Verwenden
In organic synthesis for preparation of lactams, phosphate diesters and for oxidation reactions.
synthetische
The preparation of Phenyl dichlorophosphate is as follows:160 g (1 mol) of phosphorus oxychloride and 1 g of titanium tetrachloride were respectively added to a four-necked flask to carry out the reaction, and the temperature was raised to 70-80° C., and phenol (94 g, 1 mol) was slowly added dropwise. The phenol addition time was about 2- 3 hours,After completion of the dropwise addition, the reaction is maintained at 80-90° C. for 3-5 hours. After no hydrogen chloride is evolved, the reaction is completed. After the reaction, the phosphorus oxychloride is distilled under reduced pressure, the vacuum degree is 30-100 KPa, and the distillation temperature is 30-100° C. Distillation under reduced pressure to obtain the intermediate of the mixture, a mono-substituted and di-substituted mixture of phosphorus oxychloride, the ratio of the mixture is 5:5, gas phase analysis to obtain the intermediate of the mixture, the yield of the intermediate is 95%, phosphorus oxychloride The recovery rate is 95% (calculated as phosphorus oxychloride).
Allgemeine Beschreibung
A liquid. May severely irritate skin, eyes and mucous membranes.
Air & Water Reaktionen
About the same density as water and moderately soluble in water.
Reaktivität anzeigen
An hologenated organophosphate. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Hazard
May cause severe skin, eye, and mucous membrane irritation; Reacts violently with water; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Toxic by ingestion; Highly toxic by skin absorption; Dermal LD50 (guinea pig) = 14-400 mg/kg.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Brandgefahr
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Phenyl dichlorophosphate Upstream-Materialien And Downstream Produkte

Phenyldichlorphosphat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

770-12-7, Phenyl dichlorophosphate Verwandte Suche:

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