PHENAMIL METHANESULFONATE

PHENAMIL METHANESULFONATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  off-white to yellow solid

• Verwenden

  Phenamil methanesulfonate salt has been used:
  
  • to stimulate adipocyte differentiation in 3T3 cells
  • to test its effect on lateral flagella expression in Vibrio shilonii
  • in nanoparticle preparation to test its effect on osteo/odontoblastic differentiation
  
  

• Verwenden

  Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte

• Allgemeine Beschreibung

  Phenamil, a derivative of amiloride is an inhibitor of sodium channels including acid sensing ion channel (ASIC) and epithelial sodium channels (ENaC).

• Biochem/physiol Actions

  Phenamil is an inducer of peroxisome proliferator-activated receptor γ (PPARγ) and inhibits diamine oxidase. By favoring tribbles homolog 3 (Trb3) expression, phenamil holds therapeutic potential to treat pulmonary artery hypertension (PAH) and idiopathic PAH. It is also a bone morphogenetic protein (BMP) activator, which favors osteogenesis and odontogenesis of stem cells.

• Lager

  Store at +4°C

PHENAMIL METHANESULFONATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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