PF-3893787 hydrochloride

PF-3893787 hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  Adriforant hydrochloride (PF-3893787 hydrochloride) is a novel histamine H4 receptor affinity antagonist (Ki=2.4 nM) and a functional H4 receptor antagonist (Ki=1.56 nM).

• in vitro

  Adriforant is tested and observed binding K _i =2.4 nM and functional K _i =1.56 nM for H4R. Data from functional assays produce convergent projections of the free plasma efficacious concentration and Adriforant (Compound 13) is fast on/fast off on rhH4R.

• target

  Ki: 2.4 nM (H4R bind), 1.56 nM (H4R func)

PF-3893787 hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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