Trimethylphosphin

Bezeichnung:Trimethylphosphin

CAS-Nr594-09-2

Englisch Name:Trimethylphosphine

CBNumberCB1458857

SummenformelC3H9P

Molgewicht76.08

MOL-Datei594-09-2.mol

Synonyma

Trimethylphosphin

Trimethylphosphin physikalisch-chemischer Eigenschaften

Schmelzpunkt	-86 °C (lit.)
Siedepunkt	38-40 °C (lit.)
Dichte	0.738 g/mL at 20 °C (lit.)
Dampfdruck	7.24 psi ( 20 °C)
Brechungsindex	n20/D 1.428(lit.)
Flammpunkt	−4 °F
storage temp.	2-8°C
Löslichkeit	Insoluble[in water]
Aggregatzustand	liquid
Farbe	colorless
Wichte	0.748
Wasserlöslichkeit	Soluble in water.
Sensitive	Air & Moisture Sensitive
BRN	969138
InChIKey	YWWDBCBWQNCYNR-UHFFFAOYSA-N
CAS Datenbank	594-09-2(CAS DataBase Reference)
NIST chemische Informationen	Phosphine, trimethyl-(594-09-2)

Sicherheit

Kennzeichnung gefährlicher	F,Xn,Xi
R-Sätze:	11-36/37/38-67-65-63-48/20-38-17-40-36/37-19
S-Sätze:	9-16-26-36/37/39-62-36/37-7/9-33
RIDADR	UN 1993 3/PG 2
WGK Germany	3
F	10-13-23
HazardClass	4.2
PackingGroup	I
HS Code	29319090

Gefahreninformationscode (GHS)

Trimethylphosphine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R67:Dämpfe können Schläfrigkeit und Benommenheit verursachen.
R65:Gesundheitsschädlich: kann beim Verschlucken Lungenschäden verursachen.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R48/20:Gesundheitsschädlich: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen.
R38:Reizt die Haut.
R17:Selbstentzündlich an der Luft. Spontaneously flammable in air.
S-Sätze Betriebsanweisung:
S9:Behälter an einem gut gelüfteten Ort aufbewahren.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S62:Bei Verschlucken kein Erbrechen herbeiführen. Sofort ärztlichen Rat einholen und Verpackung oder dieses Etikett vorzeigen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S7/9:Behälter dicht geschlossen an einem gut gelüfteten Ort aufbewahren.
S33:Maßnahmen gegen elektrostatische Aufladungen treffen.
Chemische Eigenschaften
Clear colorless liquid
Verwenden
Trimethylphosphine is an electron-rich phosphine ligand used in the Mitsunobu reaction. It participates in the transformation of azides into carbamates, aziridines from azidoalcohols, iminophosphoranes and aza-Wittig reaction. This product is offered as a solution in 2-methyltetrahydrofuran for more convenient handling.
Verwenden
Trimethylphosphine (PMe₃) solution is the suitable reagent used in the synthesis of Fe/Te cluster type complex, Fe₆Te₈(PMe₃)₆. It may be employed as a probe to investigate the acid sites in Y-zeolite. It may be used for the synthesis of hexakis(trimethylphosphine)tris-μ-methylene-diruthenium(III).
Verwenden
Trimethylphosphine (PMe₃) is an electron-rich phosphine ligand used as a reagent in Mitsunobu reaction.
It can be used:
- In transformation of azides into carbamates; aziridines to azidoalcohols; and ketoximes to ketones with 2,2′-dipyridyl diselenide.
- In Aza-Wittig reaction;, C-H bond activation of imines; cross-coupling reactions.
- In the preparation of (cyanomethylene) trimethylphosphorane (CMMP) which is used as a reagent in Mitsunobu type reaction.
- As a reagent in the synthesis of ruthenium trimethylphosphine complexes, which in turn are used as catalysts for hydrogenation of CO₂ to formic acid.
Definition
ChEBI: Trimethylphosphine is a tertiary phosphine.
Allgemeine Beschreibung
Trimethylphosphine is the reagent used in Mitsunobu reaction. It participates in the transformation of azides into carbamates, aziridines from azidoalcohols, iminophosphoranes and aza-Wittig reaction. Electron diffraction study of trimethylphosphine has been reported.
läuterung methode
All operations should be carried out in an efficient fume cupboard because it is flammable, toxic and has a foul odor. Distil trimethylphosphine at atmospheric pressure in a stream of dry N2 (apparatus should be held together with springs to avoid loss of gas from increased pressure in the system) and the distillate run into a solution of AgI in aqueous KI whereby the silver complex [Me3PAgI]4 separates steadily. Filter off the complex, wash it with saturated aqueous KI solution, then H2O and dry it in a vacuum desiccator over P2O5. The dry complex is heated in a flask (in a stream of dry N2) in an oil bath at 140o, when pure Me3P distils off (bath temperature can be raised up to 260o). The vapour pressure of Me3P at 20o is 466mm and the b is 37.8o [Thomas & Eriks Inorg Synth IX 59 1967]. Alternatively, freshly distilled Me3P (6g) is shaken with a solution of AgI (13.2g, 1.1mol) in saturated aqueous KI solution (50mL) for 2hours. A white solid, not wetted with H2O, separates rapidly. It is collected, washed with the KI solution, H2O, and dried [Mann et al. J Chem Soc 1829 1937]. The silver complex is stable if kept dry in the dark, in which state it can be kept indefinitely. Me3P can be generated from the complex when required. Store it under N2 in a sealed container. It has been distilled in a vacuum line at -78o in vacuo and condensed at -96o [IR and NMR: Crosbie & Sheldrick J Inorg Nucl Chem 31 3684 1969]. The pK2 2 by NMR was 8.80 [Silver & Lutz J Am Chem Soc 83 786 1961, pK2 5 8.65: Henderson & Strueuli J Am Chem Soc 82 5791 1960].

Trimethylphosphine Upstream-Materialien And Downstream Produkte

Trimethylphosphin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

594-09-2, Trimethylphosphine Verwandte Suche:

Send Inquriy