Dimethyladipat

Bezeichnung:Dimethyladipat

CAS-Nr627-93-0

Englisch Name:Dimethyl adipate

CBNumberCB1412954

SummenformelC8H14O4

Molgewicht174.19

MOL-Datei627-93-0.mol

Synonyma

Dimethyladipat

Dimethyladipat physikalisch-chemischer Eigenschaften

Schmelzpunkt	8 °C (lit.)
Siedepunkt	109-110 °C/14 mmHg (lit.)
Dichte	1.062 g/mL at 20 °C (lit.)
Dampfdruck	0.2 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.428(lit.)
FEMA	4472 \| DIMETHYL ADIPATE
Flammpunkt	225 °F
storage temp.	Store below +30°C.
Löslichkeit	<1g/l
Aggregatzustand	Liquid
Farbe	Clear
Geruch (Odor)	at 100.00 %. mild nutty
Geruchsart	nutty
Explosionsgrenze	0.81-8.1%(V)
Wasserlöslichkeit	Miscible with alcohols and ether. Immiscible with water.
Merck	14,162
JECFA Number	1964
BRN	1707443
Stabilität	Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases reducing agents.
Kosmetik-Inhaltsstoffe Funktionen	SOLVENT PLASTICISER SKIN CONDITIONING - EMOLLIENT
Erinnerung an die inhaltsstoffe	Dimethyl adipate (627-93-0)
InChI	1S/C8H14O4/c1-11-7(9)5-3-4-6-8(10)12-2/h3-6H2,1-2H3
InChIKey	UDSFAEKRVUSQDD-UHFFFAOYSA-N
SMILES	COC(=O)CCCCC(=O)OC
LogP	1.4 at 22℃
CAS Datenbank	627-93-0(CAS DataBase Reference)
NIST chemische Informationen	Hexanedioic acid, dimethyl ester(627-93-0)
EPA chemische Informationen	Dimethyl adipate (627-93-0)

Sicherheit

S-Sätze:	24/25
WGK Germany	1
RTECS-Nr.	AV1645000
Selbstentzündungstemperatur	680 °F
TSCA	TSCA listed
HS Code	29171290
Speicherklasse	10 - Combustible liquids
Giftige Stoffe Daten	627-93-0(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: 8191 mg/kg LD50 dermal Rabbit > 2250 mg/kg

Gefahreninformationscode (GHS)

Dimethyl adipate Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Dimethyl adipate (DMA) is a colourless and flammable liquid. It is soluble in alcohol and ether but sparingly soluble in water. DMA is incompatible with strong oxidising agents, and on decomposition, it emits carbon monoxide, irritating and toxic fumes and gases, and carbon dioxide. DMA reacts with acids, alkalis, and strong oxidants. DMA is synthesised by the esterification of adipic acid. DMA is part of a dibasic ester (DBE) blend used as a major ingredient in several paint strippers, and the DBE blends used in paint stripping formulations contain a major portion (about 90%) of DMA. DMA is used as a chemical intermediate (polymers, agrochemicals), cellulose resins, a speciality solvent (inks, coatings, adhesives), and an emollient and can also be utilised as a paint remover and plasticiser.
Chemische Eigenschaften
Dimethyl adipate is a colorless liquid. It is a fatty acid methyl ester.
Verwenden
Dimethyl adipate is used in cosmetics (in emollients and skin conditioning). It acts as a cosmetic plasticizer. It is also used in agrochemicals and dye as well as a precursor for the preparation of active pharmaceutical ingredients. Further, it serves as a polymer intermediate. In addition to this, it is employed as a solvent for paint stripping and resins.
Verwenden
Dimethyl adipate is used in cosmetics (in emollients and skin conditioning).It is used as a plasticizer for cellulose-type resins and a finish remover.It is also used in agrochemicals and dye as well as a precursor for the preparation of active pharmaceutical ingredients. Further, it serves as a polymer intermediate. In addition to this, it is employed as a solvent for paint stripping and resins.
Vorbereitung Methode
Dimethyl adipate is manufactured via esterification of adipic acid and methanol in the presence of an acid catalyst.
Definition
ChEBI: Dimethyl adipate is a fatty acid methyl ester.
Allgemeine Beschreibung
Colorless liquid.
Air & Water Reaktionen
Flammable. Hydrolyzed by strong mineral acids and strong alkalis.
Reaktivität anzeigen
Dimethyl adipate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Health Hazard
Exposures to dimethyl adipate cause toxicity and adverse health effects in laboratory animals and humans. Workplace exposures to dimethyl adipate by inhalation, ingestion, or skin absorption cause harmful and irritation effects to users.
Health Hazard
May be harmful by inhalation, ingestion, or skin absorption. May cause irritation.
Flammability and Explosibility
Non flammable
Sicherheitsprofil
Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
Synthese
Dimethyl adipate was synthesized by immobilized Candida antarctica lipase B-catalyzed esterification of adipic acid and methanol.

According to the general procedure described above, Dimethyl adipate has been synthesized from adipic acid (730mg, 5 mmol) and methanol (10 ml). Yield: 9%.
1H NMR (400.1 MHz, CDCl3): δ = 3.56 (6H, s, H1-H10), 2.23 (4H, m, H4-H7), 1.56 (4H, m, H5-H6).
13C NMR (100.5 MHz, CDCl3): δ = 173.4 (C3-C8), 51.2 (C1-C10), 33.4 (C4-C7), 24.1 (C5-C6)
https://pubmed.ncbi.nlm.nih.gov/20632329/
Carcinogenicity
In a chronic inhalation toxicity study of dimethyl adipate, groups of male and female rats were exposed to 400 mg/m³ of dimethyl adipate over a 90-day period. Focal respiratory metaplasia of the olfactory epithelium was found. These nonneoplastic lesions were minimal to mild in severity .
Filter für giftige stoffe
The ITSL for Dimethyl Adipate is 1 μg/m3 based on annual averaging time.
Vorsichtsmaßnahmen
During handling of dimethyl adipate, occupational workers should be careful and use self-contained breathing apparatus, rubber boots, and heavy rubber gloves and avoid prolonged period of exposures. Workers should avoid contact of dimethyl adipate with skin, eyes and nose.

Dimethyl adipate Upstream-Materialien And Downstream Produkte

Dimethyladipat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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