2,3,4-Trihydroxybenzaldehyd

Bezeichnung:2,3,4-Trihydroxybenzaldehyd

CAS-Nr2144-08-3

Englisch Name:2,3,4-Trihydroxybenzaldehyde

CBNumberCB1396755

SummenformelC7H6O4

Molgewicht154.12

MOL-Datei2144-08-3.mol

Synonyma

2,3,4-Trihydroxybenzaldehyd

2,3,4-Trihydroxybenzaldehyd physikalisch-chemischer Eigenschaften

Schmelzpunkt	159-161 °C (lit.)
Siedepunkt	237.46°C (rough estimate)
Dichte	1.3725 (rough estimate)
Brechungsindex	1.6400 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	DMSO, Methanol
pka	7.41±0.23(Predicted)
Aggregatzustand	Powder
Farbe	Light brown to beige-brown
Wasserlöslichkeit	1.541g/L at 25℃
Sensitive	Air Sensitive
BRN	2328658
LogP	1.25
CAS Datenbank	2144-08-3(CAS DataBase Reference)
EPA chemische Informationen	Benzaldehyde, 2,3,4-trihydroxy- (2144-08-3)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-37/39-36
WGK Germany	2
RTECS-Nr.	CU8439800
TSCA	Yes
HS Code	29124990

Gefahreninformationscode (GHS)

2,3,4-Trihydroxybenzaldehyde Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
2,3, 4-trihydroxybenzaldehyde is an essential intermediate of the antiparkinson drug benserazide, which is a peripheral dopa decarboxylase inhibitor, usually benserazide: the L-dopa is prepared into a compound preparation at a ratio of 1:4, and has a remarkable effect of treating the Parkinson's disease.
Chemische Eigenschaften
light brown to beige-brown powder
Verwenden
2,3,4-Trihydroxybenzaldehyde has been used in the preparation of 1,5-dimethyl-2-phenyl-4-[(1E)-(2,3,4-trihydroxybenzylidene)amino]-1H-pyrazol-3(2H)-one.
Verwenden
2,3,4-Trihydroxybenzaldehyde is a phenolic benzaldehyde with antibacterial activity.
Allgemeine Beschreibung
Antimicrobial activity of carbohydrazone derived from 2,3,4-trihydroxybenzaldehyde against bacteria and fungi has been investigated. 2,3,4-trihydroxybenzaldehyde forms Schiff bases via [1+1] condensation with anthranilic acid.
Synthese
The method for synthesizing 2,3, 4-trihydroxybenzaldehyde is shown as follows.
This method takes pyrogallol as an initial raw material. It comprises three steps of phenolic hydroxyl protection, formylation, and deprotection: protecting two adjacent phenolic hydroxyl groups in the pyrogallol to obtain 4-hydroxybenzo[d][1,3]dioxol-2-one, then performing formylation to obtain 7-hydroxy-2-oxobenzo[d][1,3]dioxole-4-carbaldehyde, and finally removing a protecting group to get a target 2,3,4-trihydroxybenzaldehyde.

2,3,4-Trihydroxybenzaldehyde Upstream-Materialien And Downstream Produkte

2,3,4-Trihydroxybenzaldehyd Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2144-08-3, 2,3,4-Trihydroxybenzaldehyde Verwandte Suche:

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