Adrenalon

Adrenalone Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Adrenalone ,Yick-Vic Chemicals and Pharmaceuticals (HK) Ltd.

• Verwenden

  Adrenergic (ophthalmic).

• Verwenden

  Adrenalone is a ketone derivative of Epinephrine (E588585) and a potential dopamine β oxidase inhibitor.

• Definition

  ChEBI: Adrenalone is an aromatic ketone.

• synthetische

  Preparation by reaction of excess 33% aqueous methylamine with 3,4-dihydroxy-a-chloroacetophenone.

• Manufacturing Process

  To a suspension of 1 part ω-chloro-3,4-dihydroxyacetophenone (prerared from chloroacetyl chloride and benzcatechole, see J. Russ. Phys. Chem. Ges., 25, 154) was added dropwise 1 part 60% solution of methylamine. Immediately was formed a residue of the salt of methylamine and ω-chloro-3,4- dihydroxyacetophenone. The dissolution of the salt was carried out by heating of the mixture. Then the salt was converted in crude 3,4-dihydroxy-α- methylaminoacetophenone. The product was dissolved in dilute hydrochloric acid. To this solution was added dropwise aqueous ammonium solution to prepare light yellow crystal of 3,4-dihydroxy-α-methylaminoacetophenone. The base and the hydrochloride of 3,4-dihydroxy-α-methylaminoacetophenone decomposed at temperature near 230°C and 240°C respectively.

• Therapeutic Function

  Hemostatic, Sympathomimetic, Vasoconstrictor

Adrenalone Upstream-Materialien And Downstream Produkte

Adrenalon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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