SCHIZOZYGINE

SCHIZOZYGINE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  The major alkaloid obtained from the bark and roots of Schizozygia caffaeoides (Boj.) Baill. The base has [α]²³_D + 15.5° (c 1.0, CHC1₃) and gives an ultraviolet spectrum having absorption maxima at 269 and 313 mil. The alkaloid possesses both antipyretic and broncholytic properties. When hydrogenated in AcOH in the presence of Pt0₂ it yields the dihydro derivative, m.p. 190-1°C;[α]²⁴_D + 29.4° (c 1.0, CHCI₃). Hydrogenation with LiAIH₄, however, gives deoxoschizozygine, m.p. 213-233°C (dec.); [α]²⁶_D + 82.9° (c 1.0, CHCI₃). The two reduction processes are protected by patents.

• Einzelnachweise

  Renner, Kernweisz., Experientia, 19,244 (1963)
  Structure:
  Renner., Lloydia, 27,406 (1964)
  Renner., Swiss Patent 451,182,15 May 1968
  Renner., Swiss Patent 451,183,15 May 1968

SCHIZOZYGINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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