Galactose

Bezeichnung:Galactose

CAS-Nr59-23-4

Englisch Name:D-Galactose

CBNumberCB1327034

SummenformelC6H12O6

Molgewicht180.16

MOL-Datei59-23-4.mol

Synonyma

Galactose

Galactose physikalisch-chemischer Eigenschaften

Schmelzpunkt	168-170 °C(lit.)
alpha	+79.0～+81.0°(D/20℃) (c=10, dil. NH4OH)
Siedepunkt	232.96°C (rough estimate)
Dichte	1,5 g/cm³
Brechungsindex	80 ° (C=10, H2O)
storage temp.	room temp
Löslichkeit	H₂O: 100 mg/mL
Aggregatzustand	powder
pka	pK1:12.35 (25°C)
Farbe	White
Geruch (Odor)	Odorless
Säure-Base-Indikators(pH-Indikatoren)	5 - 7 at 180 g/l at 25 °C
PH	4.5-6.0 (H2O)Aqueous solution
Optische Aktivität	[α]20/D +80±1°, 24 hr, c = 5% in H2O
Wasserlöslichkeit	Soluble in water.
Merck	14,4335
BRN	1724619
InChIKey	GZCGUPFRVQAUEE-DPYQTVNSSA-N
LogP	-2.490 (est)
CAS Datenbank	59-23-4(CAS DataBase Reference)
NIST chemische Informationen	D-Galactose(59-23-4)
EPA chemische Informationen	D-Galactose (59-23-4)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	22-24/25-36/37/39-27-26
WGK Germany	3
RTECS-Nr.	LW5490000
F	3
TSCA	Yes
HS Code	29400090

Gefahreninformationscode (GHS)

D-Galactose Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
D-Galactose is a monosaccharide sugar that serves as an energy source and glycosylation component. It is a C-4 epimer of glucose and often used as a source of carbon in culture media. Galactose is a component of the disaccharide lactose and released upon hydrolysis by β-galactosidase enzymes. It is converted to glucose via the Leloir pathway or metabolized via an alternative pathway, such as the DeLey-Doudoroff pathway.
Beschreibung
D-Galactose is a natural aldohexose and C-4 epimer of glucose. D-galactose is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. Chronic, systemic exposure to D-galactose accelerates senescence in invertebrates and mammals and has been used as a model for aging. In bacteria, D-galactose is imported by a methyl-galactoside transport system to drive chemotaxis.
Chemische Eigenschaften
White powder
Verwenden
D-Galactose is suitable for use in cell culture systems requiring sugar additives.
Verwenden
Galactose is a simple monosaccharide used as a component of the galactosyltransferase labeling buffer. It serves as an energy source and an important constituent of glycolipids and glycoproteins. Since it is a component of antigens, it plays a vital role in the determination of blood type within the ABO blood group system.
Verwenden
A C-4 epimer of Glucose (G595000) found in milk and sugar beets as well as being synthesized by the body. Potential use in oral therapy for nephrotic syndrome in focal and segmental glomerulosclerosis.
Application
Galactose has been used:
as a component of galactosyltransferase labeling buffer.
as a supplement in MRS broth for the growth of thermophilic lactobacilli.
to induce the expression of uncoupling protein (UCP) in yeast transformants.
Definition
A monosaccharide commonly occurring in milk sugar or lactose.
Allgemeine Beschreibung
Galactose is a constituent of lactose. It is one of the main nutrients for newborn infants and young children. It is produced in the body for the formation of lactose and is also a component of glycolipids (cerebrosides) and glycoproteins.
Biologische Aktivität
Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
Biochem/physiol Actions
Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
läuterung methode
D-Galactose is crystallised twice from aqueous 80% EtOH at -10o, then dried in a vacuum oven at 90o over P2O5 for 10hours. [Link Biochemical Preparations 3 75 1953, Hansen et al. Biochemical Preparations 4 2 1955.] Also purify it by recrystallising the dried solid (150g) in hot H2O (150mL), then adding hot MeOH (250mL) and hot EtOH (500mL), stirring to mix, filtering through a bed of charcoal, and the clear filtrate is stirred to initiate crystallisation. After standing overnight at 10o, the crystals of the -anomer are filtered off by suction, washed with MeOH, then EtOH, and dried (yield 130g), and more can be obtained by evaporation of the filtrate and washing as before. [Wolfrom & Thompson Methods in Carbohydrate Chemistry I 120 1962, Academic Press, Beilstein 1 IV 4336.]

D-Galactose Upstream-Materialien And Downstream Produkte

Galactose Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

59-23-4, D-Galactose Verwandte Suche:

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