Tetramethylharnstoff

Bezeichnung:Tetramethylharnstoff

CAS-Nr632-22-4

Englisch Name:1,1,3,3-Tetramethylurea

CBNumberCB1309805

SummenformelC5H12N2O

Molgewicht116.16

MOL-Datei632-22-4.mol

Synonyma

Tetramethylharnstoff

Tetramethylharnstoff physikalisch-chemischer Eigenschaften

Schmelzpunkt	−1 °C(lit.)
Siedepunkt	177 °C(lit.)
Dichte	0.968 g/mL at 20 °C(lit.)
Brechungsindex	n20/D 1.451(lit.)
Flammpunkt	150 °F
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	Miscible with water, petroleum ether and common solvents.
Aggregatzustand	Liquid
pka	2.0(at 25℃)
Farbe	Clear colorless to pale yellow
PH	5-8 (25℃, 1M in H2O)
Relative polarity	5
Geruch (Odor)	faint pleasant odor
Wasserlöslichkeit	H2O: 1 M at 20 °C, miscible
Merck	14,9230
BRN	773898
Dielectric constant	24.460000000000001
InChIKey	AVQQQNCBBIEMEU-UHFFFAOYSA-N
CAS Datenbank	632-22-4(CAS DataBase Reference)
NIST chemische Informationen	Urea, tetramethyl-(632-22-4)
EPA chemische Informationen	Tetramethylurea (632-22-4)

Sicherheit

Kennzeichnung gefährlicher	Xn,T
R-Sätze:	22-61
S-Sätze:	53-45
RIDADR	NA 1993 / PGIII
WGK Germany	3
RTECS-Nr.	YU2625000
F	3-10
TSCA	Yes
HS Code	29241900
Giftige Stoffe Daten	632-22-4(Hazardous Substances Data)
Toxizität	LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen)

Gefahreninformationscode (GHS)

1,1,3,3-Tetramethylurea Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
Tetramethylurea is a clear colorless to pale yellow liquid with mild aromatic odor that is miscible with water and many organic solvents. Unusual for an urea is the liquid state of tetramethylurea in a range of > 170 °C.
Verwenden
Tetramethylurea is used as a solvent in dyestuff industries, in condensation reaction and intermediates in surfactant. It is utilized for base catalyzed isomerization and alkylation hydrocyanation due to its low permittivity. It reacts with oxalyl chloride to prepare tetramethyl chloroformamidinium chloride, which is used for the conversion of carboxylic acids and dialkyl phosphates to anhydrides and pyrophosphates respectively.
synthetische
The reaction of dimethylamine with phosgene in the presence of e. g. 50 % sodium hydroxide solution and subsequent extraction with 1,2-dichloroethane yields tetramethylurea in 95% yield.
Definition
ChEBI: 1,1,3,3-tetramethylurea is a member of the class of ureas that is urea substituted by methyl groups at positions 1, 1, 3 and 3 respectively. Metabolite observed in cancer metabolism. It has a role as a human metabolite.
Sicherheitsprofil
Moderately toxic by ingestion and intravenous routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. Combustible when exposed to heat, flame, and oxidizers. To fight fire, use foam, mist, spray, dry chemicals. When heated to decomposition it emits toxic fumes of NOx.
läuterung methode
Dry it over BaO and distil it under nitrogen. It denatures proteins in H2O. [Elbaum & Herskovits Biochemistry 13 1268 1974, Kane Anal Biochem 53 350 1973, Beilstein 4 IV 225.]

1,1,3,3-Tetramethylurea Upstream-Materialien And Downstream Produkte

Tetramethylharnstoff Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

632-22-4, 1,1,3,3-Tetramethylurea Verwandte Suche:

Send Inquriy