Polygalacin D

Polygalacin D Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  White needle crystal. Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate.

• Definition

  ChEBI: Polygalacin D is a triterpenoid saponin. It has a role as a metabolite.

• Biologische Aktivität

  Polygalacin D (PGD) is a bioactive compound with anticancer and antiproliferative properties isolated from Platycodon grandiflorum. It inhibits the expression of the IAP protein family, including survivin, cIAP-1 and cIAP-2 proteins, and blocks the PI3K/Akt pathway by inhibiting GSK3β, Akt phosphorylation and PI3K expression. It induces apoptosis through the PI3K/Akt pathway.

• target

  NOS | COX | PGE | NO | NF-kB

Polygalacin D Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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