Benzoesureanhydrid

Bezeichnung:Benzoesureanhydrid

CAS-Nr93-97-0

Englisch Name:Benzoic anhydride

CBNumberCB1260942

SummenformelC14H10O3

Molgewicht226.23

MOL-Datei93-97-0.mol

Synonyma

Benzoesureanhydrid

Benzoesureanhydrid physikalisch-chemischer Eigenschaften

Schmelzpunkt	38-42 °C(lit.)
Siedepunkt	360 °C
Dichte	1.199 g/mL at 25 °C(lit.)
Brechungsindex	nD15 1.57665
Flammpunkt	>230 °F
storage temp.	Inert atmosphere,2-8°C
Löslichkeit	0.01g/l (experimental)
Aggregatzustand	Crystals or Crystalline Powder
Farbe	White to almost white
Wasserlöslichkeit	0.01 g/L
Sensitive	Moisture Sensitive
Merck	14,1092
BRN	516726
InChIKey	CHIHQLCVLOXUJW-UHFFFAOYSA-N
CAS Datenbank	93-97-0(CAS DataBase Reference)
NIST chemische Informationen	Benzoic acid, anhydride(93-97-0)
EPA chemische Informationen	Benzoic anhydride (93-97-0)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	37/38-41-36/37/38
S-Sätze:	26-39-37/39
WGK Germany	3
F	10-21
TSCA	Yes
HS Code	29163900

Gefahreninformationscode (GHS)

Benzoic anhydride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white to almost white crystals or crystalline
Verwenden
Benzoic anhydride is used as a benzoylating agent in the manufacture of pharmaceuticals, dyes and intermediates. It serves as an arylation agent in the Heck reaction. It is also used to get benzoic acid through dehydration. Further, it is used to prepare furan-2-yl-phenyl-methanone, which is similar to Friedel-Crafts acylation reaction. In addition to this, it is used for the synthesis of carboxylic esters and lactones.
Verwenden
In organic syntheses, as benzoylating agent in the manufacture of pharmaceuticals, dyes, and intermediates.
Verwenden
Benzoic Anhydride is the more active analogue of benzoic acid formed via dehydration. Benzoic Anhydride is used in the synthesis of a wide range of organic compounds including some dyes. Benzoic Anhyd ride is also used as an arylation agent in the Heck reaction.
Definition
ChEBI: Benzoic anhydride is an acyclic carboxylic anhydride. It is functionally related to a benzoic acid.
synthetische
To a flask containing 14.0 gm (0.1 mole) of benzoyl chloride and equipped with a stirrer is added 40 ml of dry dioxane and it is cooled to 5°C.Then 10 ml (0.1 mole) of dry pyridine is rapidly added at 5-10°C followed by 1.0 ml (0.056 mole) of water. After stirring for 10-15 min at 0-5°C, the reaction mixture is then poured into a mixture of 75 ml of cone, hydrochloric acid, 75 gm of cracked ice, and 350 ml of water. The product is filtered, washed first for 1 min with a cold 5% solution of sodium bicarbonate and then with water. The product is dried to afford 11.0 gm (97%), m.p. 43°C (recrystallized from a mixture of ether-petroleum ether).
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 35, p. 1262, 1987 DOI: 10.1248/cpb.35.1262
Tetrahedron Letters, 26, p. 1503, 1985 DOI: 10.1016/S0040-4039(00)98536-8
Allgemeine Beschreibung
Benzoic anhydride undergoes Friedel-Crafts acylation reaction with benzene over various ion-exchanged heteropoly acids to yield benzophenone.
läuterung methode
Free it from benzoic acid by washing with NaHCO3, then water, and drying. Crystallise it from *benzene (0.5mL/g) by adding just enough pet ether (b 40-60o) to cause cloudiness, then cool in ice. It can be distilled at 210-220o/20mm. [Beilstein 19 IV 550.]

Benzoic anhydride Upstream-Materialien And Downstream Produkte

Benzoesureanhydrid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

93-97-0, Benzoic anhydride Verwandte Suche:

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