Natriumsalicylat

Bezeichnung:Natriumsalicylat

CAS-Nr54-21-7

Englisch Name:Sodium salicylate

CBNumberCB1255762

SummenformelC7H5NaO3

Molgewicht160.1

MOL-Datei54-21-7.mol

Synonyma

Natriumsalicylat

Natriumsalicylat physikalisch-chemischer Eigenschaften

Schmelzpunkt	>300 °C (lit.)
Dichte	0.32 g/cm3 (20℃)
storage temp.	Store at +15°C to +25°C.
Löslichkeit	1000g/l
Aggregatzustand	Crystals or Crystalline Powder
Farbe	White
PH	6.5 (100g/l, H2O, 20℃)
Geruch (Odor)	wh. lustrous cryst. scales or amorphous powd., odorless or faint odor, saline taste
Wasserlöslichkeit	1000 g/L (20 ºC)
Sensitive	Light Sensitive
Merck	14,8332
BRN	3732792
Stabilität	Stable. Incompatible with mineral acids, metallic salts, iodine. May be light-sensitive.
InChIKey	ABBQHOQBGMUPJH-UHFFFAOYSA-M
LogP	2.061 (est)
CAS Datenbank	54-21-7(CAS DataBase Reference)
EPA chemische Informationen	Sodium salicylate (54-21-7)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-41-36/37/38-36
S-Sätze:	26-36
WGK Germany	1
RTECS-Nr.	VO5075000
F	8
Selbstentzündungstemperatur	>250 °C
TSCA	Yes
HS Code	29182100
Toxizität	LD50 i.p. in rats: 780 mg/kg (Goldenthal)

Gefahreninformationscode (GHS)

Sodium salicylate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R41:Gefahr ernster Augenschäden.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.
Chemische Eigenschaften
Sodium salicylate is of the salicylate family and this compound is known to trigger Reye's Syndrome in children and adults, usually following a viral infection such as influenza or chicken pox. Products containing such salicylates should not be given to children under the age of 19.
Chemische Eigenschaften
Sodium salicylate, HOC6H4COONa, is a shiny, white powder with sweetish taste and mild aromatic aroma that is soluble in water,glycerol, and alcohol.Used in medicine and as a preservative.
Verwenden
In manufacture of aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.
Verwenden
keratolytic
Verwenden
It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non - steroidal anti - inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultra violet radiation and electrons.
Definition
A salt or ester of salicylic acid.
Trademarks
Alysine (Marion Merrell Dow).
Allgemeine Beschreibung
Sodium salicylate may be prepared by the reaction, in aqueoussolution, by adding equal molar ratio of salicylic acidand sodium bicarbonate; evaporating to dryness yields thewhite salt. In solution, particularly in the presence of sodiumbicarbonate, the salt will darken on standing. This is the saltof choice for salicylate medication and usually is administeredwith sodium bicarbonate to lessen gastric distress, or itis administered in enteric coated tablets. However, the useof sodium bicarbonate is ill advised, because it decreases theplasma levels of salicylate and increases the excretion offree salicylate in the urine.
Sodium salicylate, even though not as potent as aspirinfor pain relief, also has less GI irritation and is useful for patientswho are hypersensitive to aspirin.
Biochem/physiol Actions
Cell permeable: yes
Sicherheitsprofil
Experimental poison by subcutaneous route. Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Human systemic effects by multiple and unspecified routes: toxic psychosis, excitement, respiratory stimulation, nausea or vomiting, and sweating. Experimental reproductive effects. Mutation data reported. A powerful irritant which affects the central nervous system. Incompatible with ferric salts, mineral acids, iodme, lead acetate, silver nitrate, sodium phosphate powder. When heated to decomposition it emits toxic fumes of Na2O.

Sodium salicylate Upstream-Materialien And Downstream Produkte

Natriumsalicylat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

54-21-7, Sodium salicylate Verwandte Suche:

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