Posaconazole-d4

Posaconazole-d4 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

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• Verwenden

  Orally active labelled triazole antifungal.

• Application

  Posaconazole-d4, an isotope of posaconazole, was used as an internal standard and showed retention and ionization identical to those of posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.

• Allgemeine Beschreibung

  This stable-labeled internal standard is suitable for quantification of posaconazole levels in blood, serum, or plasma by HPLC or LC-MS/MS. The antifungal posaconazole is used to treat invasive and systemic fungal infections. As a result of significant drug interactions, therapeutic drug monitoring of posaconazole is recommended when administered with protease inhibitors (PIs) or non-nucleoside reverse transcriptase inhibitors (NNRTIs).
  Liquid chromatography-mass spectrometry method for the quantification of posaconazole in human plasma: Application to pharmacokinetics following single-dose administration in the fasted state and with a high-fat meal

Posaconazole-d4 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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