4-Methylmorpholin

Bezeichnung:4-Methylmorpholin

CAS-Nr109-02-4

Englisch Name:4-Methylmorpholine

CBNumberCB1170931

SummenformelC5H11NO

Molgewicht101.15

MOL-Datei109-02-4.mol

Synonyma

4-Methylmorpholin

4-Methylmorpholin physikalisch-chemischer Eigenschaften

Schmelzpunkt	−66 °C(lit.)
Siedepunkt	115-116 °C750 mm Hg(lit.)
Dichte	0.92 g/mL at 25 °C(lit.)
Dampfdichte	>1 (vs air)
Dampfdruck	18 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.435(lit.)
Flammpunkt	75 °F
storage temp.	Store below +30°C.
Löslichkeit	Chloroform (Soluble), Ethyl Acetate, Methanol (Slightly)
Aggregatzustand	Liquid
pka	7.38(at 25℃)
Farbe	Clear
Wichte	0.920 (20/4℃)
PH	10.6 (50g/l, H2O, 20℃)
Explosionsgrenze	2.1%(V)
Wasserlöslichkeit	>500 g/L (20 ºC)
Merck	14,6277
BRN	102719
Stabilität	Volatile
InChIKey	SJRJJKPEHAURKC-UHFFFAOYSA-N
LogP	-0.32 at 25℃
CAS Datenbank	109-02-4(CAS DataBase Reference)
NIST chemische Informationen	Morpholine, 4-methyl-(109-02-4)
EPA chemische Informationen	4-Methylmorpholine (109-02-4)

Sicherheit

Kennzeichnung gefährlicher	F,C
R-Sätze:	11-20/21/22-34-10-22
S-Sätze:	16-26-36/37/39-45-25
RIDADR	UN 2535 3/PG 2
WGK Germany	1
RTECS-Nr.	QE5775000
F	10-23
Selbstentzündungstemperatur	165 °C DIN 51794
TSCA	Yes
HazardClass	3
PackingGroup	II
HS Code	29349990
Toxizität	LD50 orally in Rabbit: 1960 mg/kg LD50 dermal Rabbit 1240 mg/kg

Gefahreninformationscode (GHS)

4-Methylmorpholine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R34:Verursacht Verätzungen.
R10:Entzündlich.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S25:Berührung mit den Augen vermeiden.
Chemische Eigenschaften
colorless and transparent liquid. with characteristic odor. soluble in organic solvents, miscible with water and ethanol.
Verwenden
4-Methylmorpholine is an excellent solvent, emulsifier, corrosion inhibitor, Catalyst in polyurethane foamsextraction solvent, stabilizing agent for chlorinated hydrocarbons, and also can be used as pesticide intermediates. 4-Methylmorpholine is widely used in the synthesis of pesticide compounds such as insecticide, fungicide, plant growth regulator, etc. It is also used in the synthesis of fine chemicals such as surfactant, lubricant coolant, metal antirust agent, fiber treatment agent, etc.
synthetische
4-Methylmorpholine preparation method is to slowly add formaldehyde in morpholine drop by drop, under stirring add formic acid reaction, automatic reflux, and release carbon dioxide. After adding formic acid, heating reflux 4 ~ 5h, cooling and adding sodium hydroxide immediately distillation, collect all the fraction before the boiling point of 99 ℃, and then add sodium hydroxide in the fraction to saturation, cooling the oil layer, drying, fractional distillation, to obtain N-methylmorpholine.
Synthesis Reference(s)
Tetrahedron Letters, 36, p. 4881, 1995 DOI: 10.1016/0040-4039(95)00875-D
Allgemeine Beschreibung
4-Methylmorpholine is a water-white liquid with an ammonia-like odor. Less dense than water and insoluble in water. Flash point 75°F. May be moderately toxic by ingestion, inhalation and skin absorption. Very irritating to skin, eyes, and mucous membranes. Used as a solvent and to make pharmaceuticals.
Air & Water Reaktionen
Highly flammable. Insoluble in water.
Reaktivität anzeigen
Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Brandgefahr
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility
Flammable
läuterung methode
Dry it by refluxing with BaO or sodium, then fractionally distil it through a helices-packed column. The picrate has m 227o, the thiocyanate salt has m 103o (from butanone). [Hall J Phys Chem 60 63 1956, Beilstein 27 I 203, 27 III/IV 22.]

4-Methylmorpholine Upstream-Materialien And Downstream Produkte

4-Methylmorpholin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

109-02-4, 4-Methylmorpholine Verwandte Suche:

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