4-Nitrochinolin-N-oxid

Bezeichnung:4-Nitrochinolin-N-oxid

CAS-Nr56-57-5

Englisch Name:4-NITROQUINOLINE N-OXIDE

CBNumberCB1150485

SummenformelC9H6N2O3

Molgewicht190.16

MOL-Datei56-57-5.mol

Synonyma

4-Nitrochinolin-N-oxid

4-Nitrochinolin-N-oxid physikalisch-chemischer Eigenschaften

Schmelzpunkt	154-156 °C(lit.)
Siedepunkt	325.64°C (rough estimate)
Dichte	1.42
Brechungsindex	1.5570 (estimate)
storage temp.	-20°C
Löslichkeit	acetone: clear to hazy
pka	-1.83±0.10(Predicted)
Aggregatzustand	Crystalline Solid
Farbe	yellow to brown
BRN	165756
Stabilität	Stable. Hygroscopic, light-sensitive. Incompatible with strong oxidizing agents.
InChIKey	YHQDZJICGQWFHK-UHFFFAOYSA-N
CAS Datenbank	56-57-5(CAS DataBase Reference)
EPA chemische Informationen	4-Nitroquinoline 1-oxide (56-57-5)

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	45-68-40-20/21/22
S-Sätze:	53-45-36/37-22
RIDADR	2811
WGK Germany	3
RTECS-Nr.	VC2100000
HazardClass	6.1
PackingGroup	II
HS Code	29339900
Giftige Stoffe Daten	56-57-5(Hazardous Substances Data)
Toxizität	LD50 intraperitoneal in mouse: 190mg/kg

Gefahreninformationscode (GHS)

4-NITROQUINOLINE N-OXIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
yellow-brown crystals or powder
Verwenden
4-Nitroquinoline N-oxide has been used as a model compound to study its carcinogenic effects.
Verwenden
4-Nitroquinoline N-Oxide is used in method for constructing animal model of oral mucosal malignancy related to Kras mutation.
Definition
ChEBI: A quinoline N-oxide carrying a nitro substituent at position 4.
Allgemeine Beschreibung
Yellowish-brown plates or needles or yellow solid.
Air & Water Reaktionen
4-NITROQUINOLINE N-OXIDE is hygroscopic and light sensitive. Insoluble in water.
Reaktivität anzeigen
4-NITROQUINOLINE N-OXIDE reacts with strong oxidizing agents.
Health Hazard
ACUTE/CHRONIC HAZARDS: 4-NITROQUINOLINE N-OXIDE may cause irritation. When heated to decomposition it may emit toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides.
Brandgefahr
Flash point data for 4-NITROQUINOLINE N-OXIDE are not available; however, 4-NITROQUINOLINE N-OXIDE is probably combustible.
Biochem/physiol Actions
Skin and lung tumor initiator under experimental conditions.
Sicherheitsprofil
Suspected carcinogen with experimental carcinogenic, neoplas tigenic, and tumorigenic data. Poison by intraperitoneal and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
läuterung methode
The N-oxide recrystallises from aqueous acetone as yellow needles or platelets. [Ochiai J Org Chem 18 534 1953, Seki et al. J Phys Chem 91 126 1987, Beilstein 20 III/IV 3396.]

4-NITROQUINOLINE N-OXIDE Upstream-Materialien And Downstream Produkte

4-Nitrochinolin-N-oxid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

56-57-5, 4-NITROQUINOLINE N-OXIDE Verwandte Suche:

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