3'-Azido-3'-deoxythymidine-5'-triphosphate

3'-Azido-3'-deoxythymidine-5'-triphosphate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  3'-Azido-3'-deoxythymidine 5’-Triphosphate Tetraammonium Salt, is used for the preparation of drug against human retroviruses.

• Biologische Aktivität

  AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is an active triphosphate metabolite of Zidovudine (AZT). It has antiretroviral activity and inhibits HIV replication.

• in vitro

  AZT triphosphate causes mitochondrial dysfunction, increases the production of cytotoxic reactive oxygen species (ROS), and impairs the balance of the mitochondrial quality control system in H9c2 cell model established from rat embryonic myoblasts.

• target

  HIV
  HBV
  DNA polymerase
  Reactive oxygen species (ROS)

3'-Azido-3'-deoxythymidine-5'-triphosphate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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