ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K/J

ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K/J Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  The antibody may be used in various immunochemical techniques including enzyme linked immunosorbent assay (ELISA), immunoblotting, chromatin immunoprecipitation (ChIP), immunocytochemistry, antibody-based supershift assay and electrophoretic mobility shift assay (EMSA).

• Allgemeine Beschreibung

  Monoclonal Anti-hnRNP-K/J (mouse IgG2b isotype) is derived from the 3C2 hybridoma produced by the fusion of mouse myeloma cells (SP2/0 cells) and splenocytes from BALB/c mice immunized with hnRNP′s purified by oligo (dC) affinity chromatography.

• Biochem/physiol Actions

  Heterogeneous nuclear ribonucleoproteins (hnRNPs) act in several biological activities such as transcription, pre- mRNA processing, cytoplasmic mRNA translation and turnover. hnRNP-K is found both in the nucleus, cytoplasm, and mitochondria, therefore, it was found to be involved in many biological events in the cell like: transcription, chromatin remodeling, splicing and translation. hnRNP-K is regulated by different signaling cascades and can bind kinases. As a consequence, it can mediate signals from the cytoplasm to the nucleus.

ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K/J Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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