4-(2-(Diethylamino)-2-oxoethoxy)-3-methoxybenzolessigsäure-propylester

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  yellow oil bp0.7 210-212°C soluble in alcohol, chloroform, essentially water insoluble anasthetic Epontol (Bayer) Sombrevin

• Verwenden

  Sombrevin, is an ultra short-acting phenylacetate general anesthetic.

• Verwenden

  Anesthetic (intravenous).

• Definition

  ChEBI: Propanidid is a member of methoxybenzenes.

• Trademarks

  Epontol (Farbenfabriken Bayer A.G., Germany).

• Clinical Use

  Propanidid is used as a very short- to shortacting intravenous anesthetic for minor surgery and gynecology. It is characterized by rapid onset of and quick recovery from anesthesia, producing surgical anesthesia for 3 – 4 min. Repeated injections can be used to prolong the anesthesia. Postanesthetic sleep does not occur because the propyl ester is hydrolyzed rapidly in the patient to form inactive 3-methoxy-4- (N,N-diethylcarbamoylmethoxy)phenylacetic acid. After 20 – 30 min the patients generally are completely responsive .

• Synthese

  Propanidid , propyl 3- methoxy-4-(N,N-diethylcarbamoylmethoxy)- phenylacetate, is a colorless to pale yellowish water-insoluble oil. It is prepared from the propyl ester of sodium homovanillic acid and N,N-diethylchloroacetamide .
  

4-(2-(Diethylamino)-2-oxoethoxy)-3-methoxybenzolessigsäure-propylester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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