Sodium formaldehydesulfoxylate dihydrate

Bezeichnung:Sodium formaldehydesulfoxylate dihydrate

CAS-Nr6035-47-8

Englisch Name:Sodium formaldehydesulfoxylate dihydrate

CBNumberCB0853952

SummenformelCH7NaO4S

Molgewicht138.11

MOL-Datei6035-47-8.mol

Sodium formaldehydesulfoxylate dihydrate physikalisch-chemischer Eigenschaften

Schmelzpunkt	64-68 °C(lit.)
Dichte	1.8 g/cm3 (20℃)
Dampfdruck	2.68 hPa (20 °C)
storage temp.	Store below +30°C.
Löslichkeit	alcohol: slightly soluble(lit.)
Aggregatzustand	powder to crystal
Farbe	White to Almost white
PH	9.5-10.5 (100g/l, H2O, 20℃)
CAS Datenbank	6035-47-8(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	31-68
S-Sätze:	24/25-36/37
WGK Germany	3
RTECS-Nr.	PB0390000
HS Code	28311000
Toxizität	LD50 orally in Rabbit: 6400 mg/kg

Gefahreninformationscode (GHS)

Sodium formaldehydesulfoxylate dihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
When freshly prepared, sodium formaldehyde sulfoxylate occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.
Chemische Eigenschaften
white crystalline powder
Verwenden
Sodium hydroxymethanesulfinate dihydrate is a versatile reagent that can be used for a wide range of organic transformations such as:
- A SO₂^-2anion source for the preparation of sulfones and sultines.
- Debromination of vicinal dibromoalkanes.
- Reductive dehalogenation of aldehydes and ketones.
Verwenden
Pharmaceutic aid (preservative).
Vorbereitung Methode
Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.
Allgemeine Beschreibung
Oxidation reation of hydroxymethanesulfinic acid with chlorite has been studied in the pH range 4-8. It is a sulfur-containing reducing agent.
Pharmazeutische Anwendungen
Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.
Sicherheit(Safety)
The toxicological properties of sodium formaldehyde sulfoxylate have not been fully investigated. However, it is used in the formulation of injection products at a level to 0.1% w/v in the final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by ingestion, and when heated to decomposition it emits toxic fumes of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg
Lager
Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).
Inkompatibilitäten
Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.
Regulatory Status
Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Sodium formaldehydesulfoxylate dihydrate Upstream-Materialien And Downstream Produkte

Sodium formaldehydesulfoxylate dihydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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